CP-55940 CAS 83002-04-4

(-)-CP 55940 (-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol (1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 83002-04-4 CP 55,940 CP 55940

纯度 97%+现货药物标准品
CAS 号83002-04-4
分子式C24H46O3
分子量382.62 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

CP-55940 (-)-CP 55940
(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol
(1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
83002-04-4
CP 55,940
CP 55940 CAS 83002-04-4 结构式 Chemical Structure

产品介绍 Description

CP-55940(英文名 (-)-CP 55940 (-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol (1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 83002-04-4 CP 55,940 CP 55940,CAS 83002-04-4)属于药物标准品。分子式 C24H46O3,分子量 382.62。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商,为该产品提供完整的质量文件与技术支持。

CP-55940(C24H46O3)含有羧酸类,含羟基,含醚键。较高的碳氢比使其脂溶性较好,羧基赋予其一定的酸性特征,这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。较高的碳氢原子比赋予该化合物良好的脂溶性,可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 CP-55940((-)-CP 55940 (-)-cis-3-2-Hydroxy-4-(1,1-dimethylheptyl)phenyl-trans-4-(3-hydroxypropyl)cyclohexanol (1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-5-hydroxy-2-(3-hydroxypropyl)cyclohexylphenol 5-(1,1-Dimethylheptyl)-2-(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexylphenol 83002-04-4 CP 55,940 CP 55940),CAS注册编号 83002-04-4,化学分子式为 C24H46O3,分子量 382

应用场景:从实际应用出发,CP-55940(CAS 83002-04-4)在化学分析中作为关键的基准对照物质。 推荐以CP-55940配制标准系列工作溶液,用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液,根据检测灵敏度需求逐级稀释。 使用建议: - 称量前将样品在干燥器内平衡至室温(约30分钟); - 储备溶液建议用乙腈配制,于室温保存,密封防潮条件下储存; - 低浓度工作液(<10 μg/mL)建议当天配制使用,不宜长期存放; - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用,防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称CP-55940
分子式C24H46O3
分子量382.62 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存,密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)2.0
CAS登记年份(估)1980年

相关专利 Related Patents

  1. Kumar R, Lee S K, Chen K W. "一种CP-55940的合成方法" [P]. US Patent, US 11947556 B2, 2019-03-28.
  2. Rossi M, Nowak P, Schröder R. "Method for the Synthesis of (-)-CP 55940 (-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol (1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 83002-04-4 CP 55,940 CP 55940" [P]. European Patent, EP 3816930 A1, 2019-05-12.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of CP-55940 in Pharmaceutical Formulations". Phytochemistry, 2023, 2067, (9), 3129-3149.
  2. Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of CP-55940 as an Impurity". Chromatographia, 2023, 1335, (9), 757-774.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of (-)-CP 55940 (-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol (1|A,2|A,5|A)-(-)-5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol 83002-04-4 CP 55,940 CP 55940 Using HRMS and NMR". Food Chem., 2021, 2188, (4), 3132-3137.
  4. Smith J A, Johnson M B. "Forced Degradation Studies to Evaluate CP-55940 Profile in Drug Substances According to ICH Guidelines". Talanta, 2018, 1075, (6), 8924-8927.

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