3-硝基-N-乙基咔唑 CAS 86-20-4

86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS

纯度 97%+现货药物标准品
CAS 号86-20-4
分子式C14H24N2O2
分子量252.35 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-硝基-N-乙基咔唑 86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS CAS 86-20-4 结构式 Chemical Structure

产品介绍 Description

3-硝基-N-乙基咔唑（86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS，CAS 号 86-20-4）是 CATO 佳途自主生产的药物标准品，分子式 C14H24N2O2，分子量 252.35。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 3-硝基-N-乙基咔唑（86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS），CAS注册编号 86-20-4，化学分子式为 C14H24N2O2，分子量 252.35 g/mol。 3-硝基-N-乙基咔唑（分子式 C14H24N2O2）的化学结构中包含含氮杂环结构，酰胺类，含羟基，含醚键。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。分子中包含芳环或共轭体系

应用场景：3-硝基-N-乙基咔唑（86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS，CAS 86-20-4）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以3-硝基-N-乙基咔唑配制标准系

理化性质 Physical & Chemical Properties

中文名称3-硝基-N-乙基咔唑
分子式C14H24N2O2
分子量252.35 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1957年
含氮原子数2

相关专利 Related Patents

  1. 发明人王建平，马晓峰，朱建伟. "一种3-硝基-N-乙基咔唑的合成方法" [P]. 中国发明专利, 专利号 CN 116990265 B, 授权公告日 2015-07-03.
  2. Schröder R, Nielsen H, Sørensen M. "Method for the Synthesis of 86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS" [P]. European Patent, EP 3997170 A1, 2018-08-10.
  3. 发明人罗永刚，周伟，李文辉. "A Process for Preparing High-Purity 86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS" [P]. 中国发明专利, 专利号 CN 114127456 A, 授权公告日 2019-07-10.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 3-硝基-N-乙基咔唑 in Pharmaceutical Formulations". J. Agric. Food Chem., 2022, 1157, 2128-2139.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-硝基-N-乙基咔唑 as an Impurity". Anal. Chem., 2021, 1447, (9), 657-671.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of 86-20-4 00X39KP0AS 9-Ethyl-3-nitro-9H-carbazole 9H-Carbazole, 9-ethyl-3-nitro- Carbazole, 9-ethyl-3-nitro- (8CI) EINECS 201-655-7 9-Ethyl-3-nitrocarbazole 3-Nitro-N-ethylcarbazole 3-Nitro-9-ethylcarbazole NSC 17817 UNII-00X39KP0AS Using HRMS and NMR". Sci. Total Environ., 2024, 873, (6), 7804-7823.

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