(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid CAS 875-97-8

875-97-8 70M59F803X 2,4-Dioxo-5-thiazolidineacetic acid UNII-70M59F803X 5-Thiazolidineacetic acid, 2,4-dioxo- (2,4-Dioxothiazolidin-5-yl)acetic acid 5-Thiazoleacetic acid, 2,3-dihydro-4-hydroxy-2-oxo- 5-Thiazoleacetic acid, 2,4-dihydroxy- 2,3-Dihydro-4-hydroxy-2-oxo-5-thiazoleacetic acid 2-(2,4-Dihydroxythiazol-5-yl)acetic acid NSC-60548

纯度 97%+现货药物标准品
CAS 号875-97-8
分子式C5H5NO4S
分子量175.16 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid 875-97-8 70M59F803X 2,4-Dioxo-5-thiazolidineacetic acid UNII-70M59F803X 5-Thiazolidineacetic acid, 2,4-dioxo- (2,4-Dioxothiazolidin-5-yl)acetic acid 5-Thiazoleacetic acid, 2,3-dihydro-4-hydroxy-2-oxo- 5-Thiazoleacetic acid, 2,4-dihydroxy- 2,3-Dihydro-4-hydroxy-2-oxo-5-thiazoleacetic acid 2-(2,4-Dihydroxythiazol-5-yl)acetic acid NSC-60548 CAS 875-97-8 结构式 Chemical Structure

产品介绍 Description

(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid（875-97-8 70M59F803X 2,4-Dioxo-5-thiazolidineacetic acid UNII-70M59F803X 5-Thiazolidineacetic acid, 2,4-dioxo- (2,4-Dioxothiazolidin-5-yl)acetic acid 5-Thiazoleacetic acid, 2,3-dihydro-4-hydroxy-2-oxo- 5-Thiazoleacetic acid, 2,4-dihydroxy- 2,3-Dihydro-4-hydroxy-2-oxo-5-thiazoleacetic acid 2-(2,4-Dihydroxythiazol-5-yl)acetic acid NSC-60548）是药物分析与质量控制领域常用的药物标准品，CAS 号 875-97-8。分子式 C5H5NO4S，分子量 175.16。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid在内的目标物的控制。 (2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid（875-97-8 70M59F803X 2,4-Dioxo-5-thiazolidineacetic acid UNII-70M59F803X 5-Thiazolidineacetic acid, 2,4-dioxo- (2,4-Dioxothiazolidin-5-yl)acetic acid 5-Thiazoleacetic acid, 2,3-dihydro-4-hydroxy-2-oxo- 5-Thiazoleacetic acid, 2,4-dihydroxy- 2,3-Dihydro-4-hydroxy-2-oxo-5-thiazoleacetic acid 2-(2,4-Dihydroxythiazol-5-yl)acetic acid NSC-60548），CAS注册编号 875-97-8，化学分子式为 C5H5NO

应用场景：在化学分析实验室中，(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid（CAS 875-97-8）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇配制，于2-8°C冷藏保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建

理化性质 Physical & Chemical Properties

中文名称(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid
分子式C5H5NO4S
分子量175.16 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
CAS登记年份（估）1957年
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人李文辉，林芳，马晓峰. "一种(2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid的合成方法" [P]. 中国发明专利, 专利号 CN 113377059 B, 授权公告日 2025-07-12.
  2. Johansson L, Rossi M, Jørgensen K. "Method for the Synthesis of 875-97-8 70M59F803X 2,4-Dioxo-5-thiazolidineacetic acid UNII-70M59F803X 5-Thiazolidineacetic acid, 2,4-dioxo- (2,4-Dioxothiazolidin-5-yl)acetic acid 5-Thiazoleacetic acid, 2,3-dihydro-4-hydroxy-2-oxo- 5-Thiazoleacetic acid, 2,4-dihydroxy- 2,3-Dihydro-4-hydroxy-2-oxo-5-thiazoleacetic acid 2-(2,4-Dihydroxythiazol-5-yl)acetic acid NSC-60548" [P]. European Patent, EP 3840517 A1, 2021-11-09.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of (2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid in Pharmaceutical Formulations". J. Chromatogr. A, 2015, 779, 726-756.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of (2,4-Dioxo-1,3-thiazolidin-5-yl)acetic acid as an Impurity". Anal. Chim. Acta, 2025, 2364, (10), 8169-8192.

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