ILS-920 CAS 892494-07-4

892494-07-4 F2D5P81X82 ILS-920 UNII-F2D5P81X82 WAY-265920 ILS 920 23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)- 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-Eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-16-phenyl-23,27-epoxy-15,18-ethenopyrido(2,1-R)(1,16,2

纯度 97%+现货药物标准品
CAS 号892494-07-4
分子式C57H86N2O14
分子量1023.30 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

ILS-920 892494-07-4 F2D5P81X82 ILS-920 UNII-F2D5P81X82 WAY-265920 ILS 920 23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)- 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-Eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-16-phenyl-23,27-epoxy-15,18-ethenopyrido(2,1-R)(1,16,2 CAS 892494-07-4 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的ILS-920（892494-07-4 F2D5P81X82 ILS-920 UNII-F2D5P81X82 WAY-265920 ILS 920 23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)- 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-Eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-16-phenyl-23,27-epoxy-15,18-ethenopyrido(2,1-R)(1,16,2）为药物标准品，CAS 登记号 892494-07-4，分子式 C57H86N2O14，分子量 1023.30。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括ILS-920在内的目标物的控制。 ILS-920（892494-07-4 F2D5P81X82 ILS-920 UNII-F2D5P81X82 WAY-265920 ILS 920 23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)- 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-Eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxy

应用场景：从实际应用出发，ILS-920（CAS 892494-07-4）在化学分析中作为关键的基准对照物质。 推荐以ILS-920配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用甲醇/乙腈（1:1）为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用甲醇/乙腈（1:1）配制，于阴凉处（≤25°C）保存，避光，密封防潮条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称ILS-920
分子式C57H86N2O14
分子量1023.30 g/mol
外观形态淡黄色至黄色无定形粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）16.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
含氮原子数2

相关专利 Related Patents

  1. Williams B T, Chen K W, O'Brien P Q. "一种ILS-920的合成方法" [P]. US Patent, US 11382364 B2, 2024-09-23.
  2. 发明人陈志强，黄志刚，高志强. "Method for the Synthesis of 892494-07-4 F2D5P81X82 ILS-920 UNII-F2D5P81X82 WAY-265920 ILS 920 23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)- 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-Eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-16-phenyl-23,27-epoxy-15,18-ethenopyrido(2,1-R)(1,16,2" [P]. 中国发明专利, 专利号 CN 108435137 B, 授权公告日 2022-09-27.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of ILS-920 in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2021, 1212, 2775-2795.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of ILS-920 as an Impurity". J. Chromatogr. A, 2022, 1127, (7), 5630-5657.

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