三羟甲基甲胺基丙磺酸 钠盐 CAS 91000-53-2

91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate

纯度 97%+现货药物标准品
CAS 号91000-53-2
分子式C7H16NO6S Na
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

三羟甲基甲胺基丙磺酸 钠盐 91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate CAS 91000-53-2 结构式 Chemical Structure

产品介绍 Description

三羟甲基甲胺基丙磺酸 钠盐（91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate）是药物分析与质量控制领域常用的药物标准品，CAS 号 91000-53-2。分子式 C7H16NO6S Na。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括三羟甲基甲胺基丙磺酸 钠盐在内的目标物的控制。 CAS编号 91000-53-2 对应的化合物三羟甲基甲胺基丙磺酸 钠盐（英文标识 91000-53-2 N-Ey(oC(1/4)x>>u)(1/4)x>>u-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt (2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino-1-propanesulfonic acid sodium-potassium salt (2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{1,3-dihydroxy-2-(hydroxymethyl)propan-2-yla

应用场景：三羟甲基甲胺基丙磺酸 钠盐（91000-53-2 N- Ey(oC(1/4)x>>u)(1/4)x>>u -3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt (2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino -1-propanesulfonic acid sodium-potassium salt (2-oC>>u-1,1- paragraph signthorn(o

理化性质 Physical & Chemical Properties

中文名称三羟甲基甲胺基丙磺酸 钠盐
分子式C7H16NO6S Na
分子量265.26 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.5
CAS登记年份（估）1983年
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人杨光，孙丽萍，林芳. "一种三羟甲基甲胺基丙磺酸 钠盐的合成方法" [P]. 中国发明专利, 专利号 CN 109391067 A, 授权公告日 2018-02-10.
  2. 发明人林芳，沈红梅，陈志强. "Method for the Synthesis of 91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate" [P]. 中国发明专利, 专利号 CN 116031279 A, 授权公告日 2019-06-07.
  3. 发明人沈红梅，周伟，张德明. "A Process for Preparing High-Purity 91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate" [P]. 中国发明专利, 专利号 CN 109209510 A, 授权公告日 2020-01-28.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 三羟甲基甲胺基丙磺酸 钠盐 in Pharmaceutical Formulations". J. Sep. Sci., 2013, 385, (11), 7240-7243.
  2. Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 三羟甲基甲胺基丙磺酸 钠盐 as an Impurity". Anal. Methods, 2015, 1707, 4780-4799.
  3. Mueller T, Schmidt R K. "Identification and Structural Characterization of a Novel Degradation Product of 91000-53-2 N-[Ey(oC(1/4)x>>u)(1/4)x>>u]-3- degrees +/->>u+/-u>>CEa AAE-(1/4)ONI N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt [(2-oC>>u-1,1- paragraph signthorn(oC(1/4)x>>u)OO>>u) degrees +/->>u]-1-+/-u>>CEa AAE-(1/4)ONI potassium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate sodium 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonate Using HRMS and NMR". Molecules, 2017, 1365, 4416-4446.
  4. Kim S H, Park J Y. "Forced Degradation Studies to Evaluate 三羟甲基甲胺基丙磺酸 钠盐 Profile in Drug Substances According to ICH Guidelines". Chemosphere, 2021, 766, (2), 2010-2029.

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