AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]- CAS 947249-08-3

N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide

纯度 97%+现货药物标准品
CAS 号947249-08-3
分子式C15H20BN3O3
分子量301.15 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]- N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide CAS 947249-08-3 结构式 Chemical Structure

产品介绍 Description

CAS 947249-08-3 对应的AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]-（N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide）为 CATO 佳途药物标准品产品线成员。分子式 C15H20BN3O3，分子量 301.15。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

AcetaMide, N-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo1,2-apyridin-2-yl-的产生途径与其化学式中含氮杂环结构，酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 947249-08-3 对应的化合物AcetaMide, N-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo1,2-apyridin-2-yl-（英文标识 N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo1,2-apyridin-2-yl)acetamide），化学式 C15H20BN3O3，相对分子质量 301.15。 依据分子式为 C15H20BN3O3 的AcetaMide, N-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo1,2-apyridin-2-y

应用场景：AcetaMide, N- 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo 1,2-a pyridin-2-yl -（N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo 1,2-a pyridin-2-yl)acetamide）作为药物标准品，在化学分析分析领域承担着重要的角色。 推荐以AcetaMide, N- 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo 1,2-a pyridin-2-yl -配制标

理化性质 Physical & Chemical Properties

中文名称AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]-
分子式C15H20BN3O3
分子量301.15 g/mol
外观形态类白色至淡黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）7.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1987年
含氮原子数3

相关专利 Related Patents

  1. Johnson M A, Roberts E F, Chen K W. "一种AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]-的合成方法" [P]. US Patent, US 9365412 B2, 2020-08-12.
  2. 发明人朱建伟，徐明华，林芳. "Method for the Synthesis of N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide" [P]. 中国发明专利, 专利号 CN 109000588 A, 授权公告日 2025-01-16.
  3. 发明人杨光，孙丽萍，周伟. "A Process for Preparing High-Purity N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide" [P]. 中国发明专利, 专利号 CN 113057934 A, 授权公告日 2021-12-10.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]- in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2011, 823, (8), 5446-5464.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of AcetaMide, N-[6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)iMidazo[1,2-a]pyridin-2-yl]- as an Impurity". Sci. Total Environ., 2011, 112, 5230-5246.
  3. Smith J A, Johnson M B. "Identification and Structural Characterization of a Novel Degradation Product of N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridin-2-yl)acetamide Using HRMS and NMR". J. Sep. Sci., 2014, 1385, 6111-6140.

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