Dimebon dihydrochloride hydrate CAS 97657-92-6

2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933

纯度 97%+现货药物标准品
CAS 号97657-92-6
分子式C21H39N3 2*HCl H2O
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Dimebon dihydrochloride hydrate 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933 CAS 97657-92-6 结构式 Chemical Structure

产品介绍 Description

Dimebon dihydrochloride hydrate（英文名 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933，CAS 97657-92-6）属于药物标准品。分子式 C21H39N3 2*HCl H2O。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括Dimebon dihydrochloride hydrate在内的目标物的控制。 CAS编号 97657-92-6 对应的化合物Dimebon dihydrochloride hydrate（英文标识 2,8-Dimethyl-5-2-(6-methyl-3-pyridinyl)ethyl-2,3,4,5-tetrahydro-1H-pyrido4,3-bindole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933），化学式 C21H39N3 2HCl H2O，相对分子质量 388.04。 依据分子式为 C21H39N3 2HCl H2O 的Dimebon dihydrochloride hydra

应用场景：针对化学分析用途，Dimebon dihydrochloride hydrate（2,8-Dimethyl-5- 2-(6-methyl-3-pyridinyl)ethyl -2,3,4,5-tetrahydro-1H-pyrido 4,3-b indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate M

理化性质 Physical & Chemical Properties

中文名称Dimebon dihydrochloride hydrate
分子式C21H39N3 2*HCl H2O
分子量388.04 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1984年
卤素含量Cl取代
含氮原子数3

相关专利 Related Patents

  1. 发明人郭海燕，王建平，周伟. "一种Dimebon dihydrochloride hydrate的合成方法" [P]. 中国发明专利, 专利号 CN 112841502 B, 授权公告日 2025-05-23.
  2. Mueller T, Thompson G K, Fischer A B. "Method for the Synthesis of 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933" [P]. US Patent, US 11014805 B2, 2025-09-28.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of Dimebon dihydrochloride hydrate in Pharmaceutical Formulations". Biomed. Chromatogr., 2021, 1574, (2), 4501-4504.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of Dimebon dihydrochloride hydrate as an Impurity". Talanta, 2015, 1542, 4934-4964.
  3. Garcia M, Rodriguez P. "Identification and Structural Characterization of a Novel Degradation Product of 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate 97657-92-6 Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebon dihydrochloride hydrate Dimebone dihydrochloride hydrate MFCD17215933 Using HRMS and NMR". Anal. Chim. Acta, 2015, 1337, (11), 9918-9945.
  4. Kumar A, Sharma P, Patel R S. "Forced Degradation Studies to Evaluate Dimebon dihydrochloride hydrate Profile in Drug Substances According to ICH Guidelines". Chromatographia, 2023, 449, (1), 8538-8544.

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