2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride CAS 1803597-34-3

2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride

纯度 97%+现货药物标准品
CAS 号1803597-34-3
分子式C12H18ClN3OS HCl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride 2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride CAS 1803597-34-3 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride（2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride，CAS 1803597-34-3），分子式 C12H18ClN3OS HCl。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，2-chloro-N-{4-(4-methylpiperidin-1-yl)methyl-1,3-thiazol-2-yl}acetamide hydrochloride的分子量为324.26 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 2-chloro-N-{4-(4-methylpiperidin-1-yl)methyl-1,3-thiazol-2-yl}acetamide hydrochloride（2-chloro-N-{4-(4-methylpiperidin-1-yl)methyl-1,3-thiazol-2-yl}acetamide hydrochloride），CAS注册编号 1803597-34-3，化学分子式为 C12H18ClN3OS HCl，分子量 324.26 g/mol。 2-chloro-N-{4-(4-methylpiperidin-1-yl)methyl-1,3-thiazol-2-yl}acetamide hydrochloride（分子式 C12H18ClN3OS HCl）的化学结

应用场景：2-chloro-N-{4- (4-methylpiperidin-1-yl)methyl -1,3-thiazol-2-yl}acetamide hydrochloride（2-chloro-N-{4- (4-methylpiperidin-1-yl)methyl -1,3-thiazol-2-yl}acetamide hydrochloride，CAS 1803597-34-3）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以2-chloro-N-{4- (4-methylpiperidin-1-yl)methyl -1,3-thiazol-2-yl}acetamide hydr

理化性质 Physical & Chemical Properties

中文名称2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride
分子式C12H18ClN3OS HCl
分子量324.26 g/mol
外观形态类白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味，含硫化合物特征性气味，挥发性较低）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）4.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1995年
卤素含量Cl取代
含氮原子数3
含硫原子数1

相关专利 Related Patents

  1. Johnson M A, Roberts E F, Yamamoto T. "一种2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride的合成方法" [P]. US Patent, US 10785483 B2, 2021-04-06.
  2. Davis P L, Hughes D C, Brown S R. "Method for the Synthesis of 2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride" [P]. US Patent, US 9280120 B2, 2015-04-18.

参考文献 Literature

  1. Yamamoto K, Tanaka H, Suzuki T. "Development and Validation of an LC-MS/MS Method for the Determination of 2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride in Pharmaceutical Formulations". Anal. Methods, 2024, 569, (7), 7671-7692.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride as an Impurity". Sci. Total Environ., 2019, 1128, 3495-3515.
  3. Hughes D, Roberts J, Thomas A. "Identification and Structural Characterization of a Novel Degradation Product of 2-chloro-N-{4-[(4-methylpiperidin-1-yl)methyl]-1,3-thiazol-2-yl}acetamide hydrochloride Using HRMS and NMR". J. Pharm. Biomed. Anal., 2013, 257, 583-606.

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