的产生途径与其化学式中甾体骨架,酰胺类,含羟基,含醚键密切相关,该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。
(19992-80-4
82CYO8A460
Butixirate USAN:INN
Xenbucin trans-4-phenylcyclohexylamine salt
(1,1'-Biphenyl)-4-acetic acid, alpha-ethyl-, (+-)-, compound with trans-4-phenylcyclohexanamine (1:1)
4-Biphenylacetic acid, alpha-ethyl-, compd. with 4-phenylcyclohexylamine (1:1), trans-
Butixirate
M.G. 5771
Butixirato INN-Spanish
Butixiratum INN-Latin
EINECS 243-454-7
trans-alpha-Ethyl-4-biphenylacetic acid compd. with 4-phenylcyclohexyla
应用场景:(19992-80-4 82CYO8A460 Butixirate USAN:INN Xenbucin trans-4-phenylcyclohexylamine salt (1,1'-Biphenyl)-4-acetic acid, alpha-ethyl-, (+-)-, compound with trans-4-phenylcyclohexanamine (1:1) 4-Biphenylacetic acid, alpha-ethyl-, compd. with 4-phenylcyclohexylamine (1:1), trans- Butixirate M.G. 5771 B
理化性质 Physical & Chemical Properties
中文名称
分子式
C16H16O2 C12H17N
分子量
415.58 g/mol
外观形态
淡黄色至黄色结晶性粉末
纯度
97%+
储存条件
室温保存,避光
溶解性参考
可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性
空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射
化合物类型
药物标准品
子类
原料药标准品
不饱和度(DBE)
13.0
UV特征
有紫外吸收
结构特征
含芳环
CAS登记年份(估)
1962年
含氮原子数
1
相关专利 Related Patents
Jørgensen K, Björnsson E, Kowalski A. "一种的合成方法" [P]. European Patent, EP 3596553 A1, 2022-08-07.
发明人钱学锋,沈红梅,韩伟. "Method for the Synthesis of 19992-80-4
82CYO8A460
Butixirate [USAN:INN]
Xenbucin trans-4-phenylcyclohexylamine salt
(1,1'-Biphenyl)-4-acetic acid, alpha-ethyl-, (+-)-, compound with trans-4-phenylcyclohexanamine (1:1)
4-Biphenylacetic acid, alpha-ethyl-, compd. with 4-phenylcyclohexylamine (1:1), trans-
Butixirate
M.G. 5771
Butixirato [INN-Spanish]
Butixiratum [INN-Latin]
EINECS 243-454-7
trans-alpha-Ethyl-4-biphenylacetic acid compd. with 4-phenylcyclohexylamine (1:1)
(+-)-alpha-Ethyl-4-biphenylacetic acid, compound with trans-4-phenylcyclohexylamine (1:1)
Flectar
MG 5771
trans-4-Phenylcyclohexylamin 2-(4-biphenylyl)butyrat
Butixirato
Butixiratum
UNII-82CYO8A460" [P]. 中国发明专利, 专利号 CN 108079756 B, 授权公告日 2022-07-18.
参考文献 Literature
Chen X Y, Liu M, Zhao W Q. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Chromatographia, 2013, 1326, (2), 7507-7510.
Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Methods, 2010, 599, (7), 6766-6787.
Kowalski T, Nowak Z. "Identification and Structural Characterization of a Novel Degradation Product of 19992-80-4
82CYO8A460
Butixirate [USAN:INN]
Xenbucin trans-4-phenylcyclohexylamine salt
(1,1'-Biphenyl)-4-acetic acid, alpha-ethyl-, (+-)-, compound with trans-4-phenylcyclohexanamine (1:1)
4-Biphenylacetic acid, alpha-ethyl-, compd. with 4-phenylcyclohexylamine (1:1), trans-
Butixirate
M.G. 5771
Butixirato [INN-Spanish]
Butixiratum [INN-Latin]
EINECS 243-454-7
trans-alpha-Ethyl-4-biphenylacetic acid compd. with 4-phenylcyclohexylamine (1:1)
(+-)-alpha-Ethyl-4-biphenylacetic acid, compound with trans-4-phenylcyclohexylamine (1:1)
Flectar
MG 5771
trans-4-Phenylcyclohexylamin 2-(4-biphenylyl)butyrat
Butixirato
Butixiratum
UNII-82CYO8A460 Using HRMS and NMR". Talanta, 2025, 1241, 5751-5772.