N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin] CAS 2134-24-9
N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]
| CAS 号 | 2134-24-9 |
| 分子式 | C26H21NO3 |
| 分子量 | 395.45 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]（N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]，CAS 号 2134-24-9）是 CATO 佳途自主生产的药物标准品，分子式 C26H21NO3，分子量 395.45。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。
与同类药物标准品相比，N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin的分子量为395.45 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin（N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin），CAS注册编号 2134-24-9，化学分子式为 C26H21NO3，分子量 395.45 g/mol。 N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin（C26H21NO3）含有甾体骨架，酰胺类，含羟基，含醚键。较高的碳氢比使其脂溶性较好，羧基赋予其一定的酸性特征，这些物理化学性质直接决
应用场景：针对化学分析用途，N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin （N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin ）是具有明确定量溯源的认证级对照品。 推荐以N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester for Determination of Chymotrypsin 配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议
理化性质 Physical & Chemical Properties
| 中文名称 | N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin] |
| 分子式 | C26H21NO3 |
| 分子量 | 395.45 g/mol |
| 外观形态 | 淡黄色至黄色结晶性粉末 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO |
| 稳定性 | 空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 17.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1957年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人陈志强，徐明华，沈红梅. "一种N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]的合成方法" [P]. 中国发明专利, 专利号 CN 108488973 A, 授权公告日 2017-03-17.
- 发明人周伟，沈红梅，徐明华. "Method for the Synthesis of N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]" [P]. 中国发明专利, 专利号 CN 115527750 A, 授权公告日 2023-10-05.
- 发明人郭海燕，张德明，韩伟. "A Process for Preparing High-Purity N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin]" [P]. 中国发明专利, 专利号 CN 114258598 A, 授权公告日 2017-08-17.
参考文献 Literature
- Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin] in Pharmaceutical Formulations". Phytochemistry, 2017, 1699, (3), 8101-8119.
- Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester [for Determination of Chymotrypsin] as an Impurity". Environ. Sci. Technol., 2024, 1615, (3), 5442-5464.
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