3-羟基苯硼酸频哪醇酯 CAS 214360-76-6

214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester

纯度 97%+现货药物标准品
CAS 号214360-76-6
分子式C12H23BO3
分子量226.12 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-羟基苯硼酸频哪醇酯 214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester CAS 214360-76-6 结构式 Chemical Structure

产品介绍 Description

CAS 214360-76-6 对应的3-羟基苯硼酸频哪醇酯（214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester）为 CATO 佳途药物标准品产品线成员。分子式 C12H23BO3，分子量 226.12。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

CAS编号 214360-76-6 对应的化合物3-羟基苯硼酸频哪醇酯（英文标识 214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester），化学式 C12H23BO3，相对分子质量 226.12。 依据分子式为 C12H23BO3 的3-羟基苯硼酸频哪醇酯结构特征，其分子内含羧酸类，含羟基，含醚键，这意味着该化合物在红外光谱中会呈现特征性的官能团伸缩振动信号

应用场景：3-羟基苯硼酸频哪醇酯（214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic aci

理化性质 Physical & Chemical Properties

中文名称3-羟基苯硼酸频哪醇酯
分子式C12H23BO3
分子量226.12 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，密封防潮
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）2018年

相关专利 Related Patents

  1. Hughes D C, Davis P L, Brown S R. "一种3-羟基苯硼酸频哪醇酯的合成方法" [P]. US Patent, US 10385867 B2, 2021-11-16.
  2. 发明人陈志强，郑宇鹏，沈红梅. "Method for the Synthesis of 214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester" [P]. 中国发明专利, 专利号 CN 117895840 B, 授权公告日 2015-10-13.
  3. 发明人沈红梅，徐明华，陈志强. "A Process for Preparing High-Purity 214360-76-6 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-phenol 3-(4,4,5,5-tetramethyl-1,3,2,dioxaborolan-2-yl)phenol 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-hydroxybenzeneboronic acid pinacol ester 3-hydroxybenzeneboronic acid, pinacol ester 3-hydroxyphenylboronic acid pinacol ester 3-hydroxyphenylboronic acid, pinacol ester" [P]. 中国发明专利, 专利号 CN 117520620 A, 授权公告日 2023-11-18.

参考文献 Literature

  1. Kowalski T, Nowak Z. "Development and Validation of an LC-MS/MS Method for the Determination of 3-羟基苯硼酸频哪醇酯 in Pharmaceutical Formulations". Sci. Total Environ., 2018, 1975, 6659-6674.
  2. Smith J A, Johnson M B. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-羟基苯硼酸频哪醇酯 as an Impurity". Rapid Commun. Mass Spectrom., 2019, 2293, (4), 5610-5636.

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