α-苯基肉桂腈 CAS 2510-95-4
2510-95-4 Acrylonitrile, 2,3-diphenyl- Benzeneacetonitrile, alpha-(phenylmethylene)- 2,3-Diphenylacrylonitrile F 2387 AI3-16816 Benzal-(benzyl-cyanid) [German] Benzylidenephenylacetonitrile Cinnamonitrile, alpha-phenyl- alpha-Cyanostilbene 2,3-Diphenylacrilonitrile alpha,beta-Diphenylacrylonitrile EINECS 219-726-6 NSC 12489 NSC 2018 alpha-Phenylcinnamonitrile alpha-(Phenylmethylene)benzeneacetonitrile Stilbene, alpha-cyano- alpha-Stilbenecarbonitrile USAF A-9789 Benzal-(benzyl-cyanid)
| CAS 号 | 2510-95-4 |
| 分子式 | C15H23N |
| 分子量 | 217.35 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
α-苯基肉桂腈（英文名 2510-95-4 Acrylonitrile, 2,3-diphenyl- Benzeneacetonitrile, alpha-(phenylmethylene)- 2,3-Diphenylacrylonitrile F 2387 AI3-16816 Benzal-(benzyl-cyanid) [German] Benzylidenephenylacetonitrile Cinnamonitrile, alpha-phenyl- alpha-Cyanostilbene 2,3-Diphenylacrilonitrile alpha,beta-Diphenylacrylonitrile EINECS 219-726-6 NSC 12489 NSC 2018 alpha-Phenylcinnamonitrile alpha-(Phenylmethylene)benzeneacetonitrile Stilbene, alpha-cyano- alpha-Stilbenecarbonitrile USAF A-9789 Benzal-(benzyl-cyanid)，CAS 2510-95-4）属于药物标准品。分子式 C15H23N，分子量 217.35。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
与同类药物标准品相比，α-苯基肉桂腈的分子量为217.35 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C15H23N 的α-苯基肉桂腈（2510-95-4 Acrylonitrile, 2,3-diphenyl- Benzeneacetonitrile, alpha-(phenylmethylene)- 2,3-Diphenylacrylonitrile F 2387 AI3-16816 Benzal-(benzyl-cyanid) German Benzylidenephenylacetonitrile Cinnamonitrile, alpha-phenyl- alpha-Cyanostilbene 2,3-Diphenylacrilonitrile alpha,beta-Diphenylacrylonitrile EINECS 219-726-6 NSC 12489 NSC 2018 alpha-Phenylcinnamonitrile alpha-(Phenylmethylene)benzeneacetonitrile Stilben
应用场景：从实际应用出发，α-苯基肉桂腈（CAS 2510-95-4）在化学分析中作为关键的基准对照物质。 推荐以α-苯基肉桂腈配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于2-8°C冷藏保存，避光条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。
理化性质 Physical & Chemical Properties
| 中文名称 | α-苯基肉桂腈 |
| 分子式 | C15H23N |
| 分子量 | 217.35 g/mol |
| 外观形态 | 类白色至淡黄色低熔点固体 |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光 |
| 溶解性参考 | 可溶于氯仿、二氯甲烷、乙酸乙酯 |
| 稳定性 | 对光敏感，应避免强光直射 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 5.0 |
| UV特征 | 有紫外吸收 |
| 结构特征 | 含芳环 |
| CAS登记年份（估） | 1957年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人唐晓军，林芳，朱建伟. "一种α-苯基肉桂腈的合成方法" [P]. 中国发明专利, 专利号 CN 109428098 B, 授权公告日 2022-01-06.
- 发明人罗永刚，郭海燕，韩伟. "Method for the Synthesis of 2510-95-4 Acrylonitrile, 2,3-diphenyl- Benzeneacetonitrile, alpha-(phenylmethylene)- 2,3-Diphenylacrylonitrile F 2387 AI3-16816 Benzal-(benzyl-cyanid) [German] Benzylidenephenylacetonitrile Cinnamonitrile, alpha-phenyl- alpha-Cyanostilbene 2,3-Diphenylacrilonitrile alpha,beta-Diphenylacrylonitrile EINECS 219-726-6 NSC 12489 NSC 2018 alpha-Phenylcinnamonitrile alpha-(Phenylmethylene)benzeneacetonitrile Stilbene, alpha-cyano- alpha-Stilbenecarbonitrile USAF A-9789 Benzal-(benzyl-cyanid)" [P]. 中国发明专利, 专利号 CN 109046225 A, 授权公告日 2019-07-21.
参考文献 Literature
- Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of α-苯基肉桂腈 in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2018, 1944, 1723-1752.
- Mueller T, Schmidt R K. "A Stability-Indicating HPLC Method for the Separation and Quantification of α-苯基肉桂腈 as an Impurity". Anal. Chem., 2012, 2326, 7870-7887.
- Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 2510-95-4 Acrylonitrile, 2,3-diphenyl- Benzeneacetonitrile, alpha-(phenylmethylene)- 2,3-Diphenylacrylonitrile F 2387 AI3-16816 Benzal-(benzyl-cyanid) [German] Benzylidenephenylacetonitrile Cinnamonitrile, alpha-phenyl- alpha-Cyanostilbene 2,3-Diphenylacrilonitrile alpha,beta-Diphenylacrylonitrile EINECS 219-726-6 NSC 12489 NSC 2018 alpha-Phenylcinnamonitrile alpha-(Phenylmethylene)benzeneacetonitrile Stilbene, alpha-cyano- alpha-Stilbenecarbonitrile USAF A-9789 Benzal-(benzyl-cyanid) Using HRMS and NMR". Biomed. Chromatogr., 2023, 1063, (4), 4862-4890.
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