Mueller T, Yamamoto T, Fischer A B. "一种3-Chloro-2-methylphenol的合成方法" [P]. US Patent, US 9122587 B2, 2021-03-25.
发明人冯建国,周伟,胡光. "Method for the Synthesis of (3-METHOXYPHENYL)ACETONITRILE
(M-METHOXYPHENYL)ACETONITRILE
2-(3-METHOXYPHENYL)ACETONITRILE
3-(CYANOMETHYL)ANISOLE
3-Chloro-2-methylphenol
3-METHOXYBENZYL CYANIDE
3260-87-5
AS02821
M-METHOXYBENZYL CYANIDE
OTAVA-BB 1287078
PARAGOS 510024
PHARMABRIDGE P-2049
PHENOL, 3-CHLORO-2-METHYL-" [P]. 中国发明专利, 专利号 CN 115025112 A, 授权公告日 2025-12-08.
参考文献 Literature
Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 3-Chloro-2-methylphenol in Pharmaceutical Formulations". Biomed. Chromatogr., 2011, 2055, (4), 9811-9823.
Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-Chloro-2-methylphenol as an Impurity". J. Agric. Food Chem., 2021, 1158, (6), 925-936.
Martinez C, Lopez D R. "Identification and Structural Characterization of a Novel Degradation Product of (3-METHOXYPHENYL)ACETONITRILE
(M-METHOXYPHENYL)ACETONITRILE
2-(3-METHOXYPHENYL)ACETONITRILE
3-(CYANOMETHYL)ANISOLE
3-Chloro-2-methylphenol
3-METHOXYBENZYL CYANIDE
3260-87-5
AS02821
M-METHOXYBENZYL CYANIDE
OTAVA-BB 1287078
PARAGOS 510024
PHARMABRIDGE P-2049
PHENOL, 3-CHLORO-2-METHYL- Using HRMS and NMR". Molecules, 2019, 2378, (10), 5611-5637.
Fischer P, Wagner E. "Forced Degradation Studies to Evaluate 3-Chloro-2-methylphenol Profile in Drug Substances According to ICH Guidelines". Anal. Chim. Acta, 2015, 1039, 5977-5983.