1-溴-4-(三氟甲氧基)苯 CAS 407-14-7
1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROANISOLE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE 4-BROMOA-TRIFLUOROMETHOXYBENZENE 4-BROMOBENZOTRIFLUORIDE 4-BROMOTRIFLUOROTOLUENE 407-14-7 AS00244 BENZENE, 1-BROMO-4-(TRIFLUOROMETHYL)- P-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE P-BROMOBENZOTRIFLUORIDE P-BROMOTRIFLUOROMETHOXYBENZENE P-BROMOTRIFLUOROMETHYLBENZENE P-TRIFLUOROMETHOXY BROMOBENZENE TIMTEC-BB SBB006606
| CAS 号 | 407-14-7 |
| 分子式 | C7H10BrF3O |
| 分子量 | 247.05 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
1-溴-4-(三氟甲氧基)苯（英文名 1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROANISOLE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE 4-BROMOA-TRIFLUOROMETHOXYBENZENE 4-BROMOBENZOTRIFLUORIDE 4-BROMOTRIFLUOROTOLUENE 407-14-7 AS00244 BENZENE, 1-BROMO-4-(TRIFLUOROMETHYL)- P-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE P-BROMOBENZOTRIFLUORIDE P-BROMOTRIFLUOROMETHOXYBENZENE P-BROMOTRIFLUOROMETHYLBENZENE P-TRIFLUOROMETHOXY BROMOBENZENE TIMTEC-BB SBB006606，CAS 407-14-7）属于药物标准品。分子式 C7H10BrF3O，分子量 247.05。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。
在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括1-溴-4-(三氟甲氧基)苯在内的目标物的控制。 化学式为 C7H10BrF3O 的1-溴-4-(三氟甲氧基)苯（1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROANISOLE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE 4-BROMOA-TRIFLUOROMETHOXYBENZENE 4-BROMOBENZOTRIFLUORIDE 4
应用场景：1-溴-4-(三氟甲氧基)苯（1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALP
理化性质 Physical & Chemical Properties
| 中文名称 | 1-溴-4-(三氟甲氧基)苯 |
| 分子式 | C7H10BrF3O |
| 分子量 | 247.05 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有轻微卤代物特征气味，挥发性较低） |
| 纯度 | 97%+ |
| 储存条件 | 室温保存，密闭保存防止挥发 |
| 溶解性参考 | 可溶于甲醇、乙腈、DMSO、水（微溶） |
| 稳定性 | 在推荐条件下性质稳定 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | 1.0 |
| CAS登记年份（估） | 1957年 |
| 卤素含量 | F/Br取代 |
相关专利 Related Patents
- 发明人罗永刚，张德明，沈红梅. "一种1-溴-4-(三氟甲氧基)苯的合成方法" [P]. 中国发明专利, 专利号 CN 113041133 A, 授权公告日 2022-01-18.
- Yamamoto T, Klinger H, Williams B T. "Method for the Synthesis of 1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROANISOLE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE 4-BROMOA-TRIFLUOROMETHOXYBENZENE 4-BROMOBENZOTRIFLUORIDE 4-BROMOTRIFLUOROTOLUENE 407-14-7 AS00244 BENZENE, 1-BROMO-4-(TRIFLUOROMETHYL)- P-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE P-BROMOBENZOTRIFLUORIDE P-BROMOTRIFLUOROMETHOXYBENZENE P-BROMOTRIFLUOROMETHYLBENZENE P-TRIFLUOROMETHOXY BROMOBENZENE TIMTEC-BB SBB006606" [P]. US Patent, US 10711628 B2, 2018-01-11.
- 发明人林芳，沈红梅，马晓峰. "A Process for Preparing High-Purity 1-BROMO-4-(TRIFLUOROMETHYL)BENZENE 1-BROMO-4-(TRIFLUOROMETHYL)BENZOLE 1-Bromo-4-(trifluoromethoxy)benzene 4-(TRIFLUOROMETHOXY)BROMOBENZENE 4-(TRIFLUOROMETHYL)BROMOBENZENE 4-BROMO(TRIFLUOROMETHOXY)BENZENE 4-BROMO-1-TRIFLUOROMETHYLBENZENE 4-BROMO-A,A,A-TRIFLUOROTOLUENE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROANISOLE 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE 4-BROMOA-TRIFLUOROMETHOXYBENZENE 4-BROMOBENZOTRIFLUORIDE 4-BROMOTRIFLUOROTOLUENE 407-14-7 AS00244 BENZENE, 1-BROMO-4-(TRIFLUOROMETHYL)- P-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE P-BROMOBENZOTRIFLUORIDE P-BROMOTRIFLUOROMETHOXYBENZENE P-BROMOTRIFLUOROMETHYLBENZENE P-TRIFLUOROMETHOXY BROMOBENZENE TIMTEC-BB SBB006606" [P]. 中国发明专利, 专利号 CN 108562316 A, 授权公告日 2023-06-20.
参考文献 Literature
- O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 1-溴-4-(三氟甲氧基)苯 in Pharmaceutical Formulations". Talanta, 2025, 423, (2), 7746-7753.
- Xu M, Hu Y, Zhou D. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-溴-4-(三氟甲氧基)苯 as an Impurity". Rapid Commun. Mass Spectrom., 2021, 1946, 4481-4510.
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