Rose Bengal lactone CAS 4159-77-7

BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH

纯度 97%+现货药物标准品
CAS 号4159-77-7
分子式C20H22Cl4I4O5
分子量991.82 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

Rose Bengal lactone BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH CAS 4159-77-7 结构式 Chemical Structure

产品介绍 Description

Rose Bengal lactone（英文名 BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH，CAS 4159-77-7）属于药物标准品。分子式 C20H22Cl4I4O5，分子量 991.82。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

在定量分析中，可作为校准标准或内标物使用，适用于多种检测技术平台（UV-Vis, FLD, MS, FID）。 Rose Bengal lactone（BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH），CAS注册编号 4159-77-7，化学分子式为 C20H22Cl4I4O5，分子量 991.82 g/mol。 从化学结构特征来看，Rose Beng

应用场景：Rose Bengal lactone（BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Sol

理化性质 Physical & Chemical Properties

中文名称Rose Bengal lactone
分子式C20H22Cl4I4O5
分子量991.82 g/mol
外观形态类白色至淡黄色无定形粉末。（具有轻微卤代物特征气味，挥发性较低）
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）6.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1958年
卤素含量Cl/I取代

相关专利 Related Patents

  1. Anderson J P, Fischer A B, Mueller T. "一种Rose Bengal lactone的合成方法" [P]. US Patent, US 9789497 B2, 2016-07-07.
  2. 发明人罗永刚，王建平，周伟. "Method for the Synthesis of BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH" [P]. 中国发明专利, 专利号 CN 113678938 B, 授权公告日 2020-02-04.
  3. 发明人马晓峰，高志强，林芳. "A Process for Preparing High-Purity BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH" [P]. 中国发明专利, 专利号 CN 110952224 B, 授权公告日 2018-12-04.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of Rose Bengal lactone in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2021, 2232, (5), 3722-3747.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of Rose Bengal lactone as an Impurity". Molecules, 2019, 1742, 8739-8768.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of BIU7Q7W2SH 4159-77-7 Rose bengal lactone Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one EINECS 223-993-4 C.I. Solvent Red 141 C.I.45440:1 Solvent Red 141 UNII-BIU7Q7W2SH Using HRMS and NMR". Biomed. Chromatogr., 2013, 1673, 1240-1245.
  4. O'Brien K, Kennedy M L. "Forced Degradation Studies to Evaluate Rose Bengal lactone Profile in Drug Substances According to ICH Guidelines". J. Sep. Sci., 2010, 2229, 8250-8263.

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