(氰甲基)三苯基氯化膦 CAS 4336-70-3

(Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride

纯度 97%+现货药物标准品
CAS 号4336-70-3
分子式C20H35NP Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(氰甲基)三苯基氯化膦 (Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride CAS 4336-70-3 结构式 Chemical Structure

产品介绍 Description

(氰甲基)三苯基氯化膦（(Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride）是药物分析与质量控制领域常用的药物标准品，CAS 号 4336-70-3。分子式 C20H35NP Cl。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

作为认证标准物质（CRM），(氰甲基)三苯基氯化膦满足CNAS-CL04（ISO/IEC 17025）对标准物质的计量溯源性要求。批间一致性通过控制图（Control Chart）进行持续监控，保证不同批次间量值的一致性。 化学式为 C20H35NP Cl 的(氰甲基)三苯基氯化膦（(Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride），其CAS登记号是 4336-70-3，分子量为 355.93 g/mol。 从化学结构特征来看，(氰甲基)三苯基氯化膦的分子骨架中包含含氰基，有机磷，含氯取代。该

应用场景：针对化学分析用途，(氰甲基)三苯基氯化膦（(Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride）是具有明确定量溯源的认证级

理化性质 Physical & Chemical Properties

中文名称(氰甲基)三苯基氯化膦
分子式C20H35NP Cl
分子量355.93 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1958年
卤素含量Cl取代
含氮原子数1

相关专利 Related Patents

  1. Rossi M, Björnsson E, Sørensen M. "一种(氰甲基)三苯基氯化膦的合成方法" [P]. European Patent, EP 3298299 A1, 2015-11-11.
  2. 发明人杨光，张德明，唐晓军. "Method for the Synthesis of (Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride" [P]. 中国发明专利, 专利号 CN 112764859 A, 授权公告日 2025-09-19.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of (氰甲基)三苯基氯化膦 in Pharmaceutical Formulations". Anal. Chim. Acta, 2012, 2343, (9), 6216-6234.
  2. Kim S H, Park J Y. "A Stability-Indicating HPLC Method for the Separation and Quantification of (氰甲基)三苯基氯化膦 as an Impurity". J. Chromatogr. A, 2012, 493, 6700-6711.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of (Cyanomethyl)triphenylphosphonium chloride (Cyanomethyl)triphenylphosphonium- (Triphenylphosphoranyl)acetonitrile 2-(triphenyl-$l^{5}-phosphanylidene)acetonitrile 4336-70-3 NSC92174 Phosphonium, (cyanomethyl)triphenyl- Phosphonium, (cyanomethyl)triphenyl-, chloride Using HRMS and NMR". Molecules, 2013, 2439, (1), 8327-8352.

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