对苯二甲胺 CAS 539-48-0

539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen [Czech] 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine [Czech] p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendiamine 1,4-Xylenediamine UNII-FJD90IO4NH

纯度 97%+现货药物标准品
CAS 号539-48-0
分子式C8H18N2
分子量142.24 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

对苯二甲胺 539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen [Czech] 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine [Czech] p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendiamine 1,4-Xylenediamine UNII-FJD90IO4NH CAS 539-48-0 结构式 Chemical Structure

产品介绍 Description

CAS 539-48-0 对应的对苯二甲胺（539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen [Czech] 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine [Czech] p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendiamine 1,4-Xylenediamine UNII-FJD90IO4NH）为 CATO 佳途药物标准品产品线成员。分子式 C8H18N2，分子量 142.24。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

与同类药物标准品相比，对苯二甲胺的分子量为142.24 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 CAS编号 539-48-0 对应的化合物对苯二甲胺（英文标识 539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen Czech 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine Czech p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendi

应用场景：针对化学分析用途，对苯二甲胺（539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen Czech 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-

理化性质 Physical & Chemical Properties

中文名称对苯二甲胺
分子式C8H18N2
分子量142.24 g/mol
外观形态白色至类白色液体。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.0
CAS登记年份（估）1957年
含氮原子数2

相关专利 Related Patents

  1. 发明人韩伟，徐明华，朱建伟. "一种对苯二甲胺的合成方法" [P]. 中国发明专利, 专利号 CN 110946383 A, 授权公告日 2022-05-10.
  2. Johansson L, Kowalski A, Lefèvre J P. "Method for the Synthesis of 539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen [Czech] 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine [Czech] p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendiamine 1,4-Xylenediamine UNII-FJD90IO4NH" [P]. European Patent, EP 3907759 A1, 2021-02-18.
  3. 发明人朱建伟，黄志刚，杨光. "A Process for Preparing High-Purity 539-48-0 FJD90IO4NH 1,4-Benzenedimethanamine Methylamine, p-phenylenebis- p-Phenylenebis(methylamine) 4-13-00-00296 (Beilstein Handbook Reference) 4-Aminomethylbenzylamine 1,4-Bis-aminomethylbenzen [Czech] 1,4-Bis(aminomethyl)benzene BRN 2206190 EINECS 208-719-3 p-Xylene-alpha,alpha'-diamine p-Xylylendiamine [Czech] p-Xylylenediamine 1,4-Xylylenediamine CCRIS 6170 1,4-Bis-aminomethylbenzen p-Xylylendiamine 1,4-Xylenediamine UNII-FJD90IO4NH" [P]. 中国发明专利, 专利号 CN 112678141 A, 授权公告日 2017-02-14.

参考文献 Literature

  1. O'Brien K, Kennedy M L. "Development and Validation of an LC-MS/MS Method for the Determination of 对苯二甲胺 in Pharmaceutical Formulations". Anal. Chem., 2010, 1506, (12), 3704-3712.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 对苯二甲胺 as an Impurity". Anal. Chim. Acta, 2010, 873, 7476-7482.

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