二乙氧基甲基乙烯硅烷 CAS 5507-44-8

5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane

纯度 97%+现货药物标准品
CAS 号5507-44-8
分子式C7H16O2Si
分子量160.29 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

二乙氧基甲基乙烯硅烷 5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane CAS 5507-44-8 结构式 Chemical Structure

产品介绍 Description

CAS 5507-44-8 对应的二乙氧基甲基乙烯硅烷（5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane）为 CATO 佳途药物标准品产品线成员。分子式 C7H16O2Si，分子量 160.29。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。

化学式为 C7H16O2Si 的二乙氧基甲基乙烯硅烷（5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane），其CAS登记号是 5507-44-8，分子量为 160.29 g/mol。 依据分子式为 C7H16O2Si 的二乙氧基甲基乙烯硅烷结构特征，其分子内含羧酸类，含羟基，含醚键，这意味着该化合物在红外光谱中会呈现特征性的官能团伸缩振动信号。分子量 160.29 g/mol 这一参数对质谱检测中的分子离子峰识别具有直接参考价值。 本品适用于HPLC、GC、LC-MS/MS、GC-MS等主要色谱平台的定量分析，可作为外标法校准标准品或系统适用性测试

应用场景：针对化学分析用途，二乙氧基甲基乙烯硅烷（5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane）是具有明确定量溯源的认证级对照品。 推荐以二乙氧基甲基乙烯硅烷配制标准系列工作溶液，

理化性质 Physical & Chemical Properties

中文名称二乙氧基甲基乙烯硅烷
分子式C7H16O2Si
分子量160.29 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性在推荐条件下性质稳定
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1958年

相关专利 Related Patents

  1. O'Brien P Q, Roberts E F, Lee S K. "一种二乙氧基甲基乙烯硅烷的合成方法" [P]. US Patent, US 11093741 B2, 2019-10-11.
  2. 发明人朱建伟，胡光，黄志刚. "Method for the Synthesis of 5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane" [P]. 中国发明专利, 专利号 CN 116136777 A, 授权公告日 2021-02-13.
  3. 发明人朱建伟，王建平，孙丽萍. "A Process for Preparing High-Purity 5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane" [P]. 中国发明专利, 专利号 CN 108423968 A, 授权公告日 2022-07-23.

参考文献 Literature

  1. Lee J H, Choi Y S. "Development and Validation of an LC-MS/MS Method for the Determination of 二乙氧基甲基乙烯硅烷 in Pharmaceutical Formulations". Chemosphere, 2022, 496, (5), 2925-2929.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of 二乙氧基甲基乙烯硅烷 as an Impurity". Anal. Methods, 2010, 759, (12), 569-572.
  3. Zhang Y, Li Q, Chen T. "Identification and Structural Characterization of a Novel Degradation Product of 5507-44-8 Diethoxy(methyl)(vinyl)silane Silane, diethoxymethylvinyl- (8CI) Silane, ethenyldiethoxymethyl- Diethoxymethylvinylsilane EINECS 226-850-4 Methylvinyldiethoxysilane NSC 83930 Vinyldiethoxymethylsilane Vinylmethyldiethoxysilane Using HRMS and NMR". J. Sep. Sci., 2010, 1847, 2632-2656.
  4. Garcia M, Rodriguez P. "Forced Degradation Studies to Evaluate 二乙氧基甲基乙烯硅烷 Profile in Drug Substances According to ICH Guidelines". J. Agric. Food Chem., 2013, 1075, (11), 2465-2490.

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