(<I>R,R</I>)-DIPAMP CAS 55739-58-7

(R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064

纯度 97%+现货药物标准品
CAS 号55739-58-7
分子式C28H52O2P2
分子量482.66 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

(<I>R,R</I>)-DIPAMP (R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064 CAS 55739-58-7 结构式 Chemical Structure

产品介绍 Description

(<I>R,R</I>)-DIPAMP（(R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064）是药物分析与质量控制领域常用的药物标准品，CAS 号 55739-58-7。分子式 C28H52O2P2，分子量 482.66。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括(<I>R,R</I>)-DIPAMP在内的目标物的控制。 CAS编号 55739-58-7 对应的化合物(<I>R,R</I>)-DIPAMP（英文标识 (R,R)-(-)-1,2-Bis(2-methoxyphenyl)(phenyl)phosphinoethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS(2-METHOXYPHENYL)PHENYLPHOSPHINOETHANE;(R,R)-(-)-1,2-BIS(2-METHOXYPHENYL)(PHENYL)PHOSPHINOETHANE;(R,R)-1,2-BIS(2-METHOXYPHENYL)PHENYLPHOSPHINOETHANE;(R,R)-1,2-BIS(O-METHOXYPHENYL)PHENYLPHOSPHINOETHANE;(R,R)-1,2-ETHANEDIYLBIS(2-METHOXYPHENYL)PHENYLPHOSPHINE;(R,R)-DIPAMP;(R,R)-ETHYLENEBIS

应用场景：在化学分析实验室中，(<I>R,R</I>)-DIPAMP（CAS 55739-58-7）凭借其97%+的纯度做为基础物质，为定量分析提供基准参照。 推荐以(<I>R,R</I>)-DIPAMP配制标准系列工作溶液，用于建立标准曲线实现外标法定量。 建议使用乙腈为溶剂配制储备溶液，根据检测灵敏度需求逐级稀释。 使用建议： - 称量前将样品在干燥器内平衡至室温（约30分钟）； - 储备溶液建议用乙腈配制，于室温保存条件下储存； - 低浓度工作液（<10 μg/mL）建议当天配制使用，不宜长期存放； - 开启安瓿瓶/西林瓶后应在干燥环境下尽快使用，防止吸潮影响称量准确性。

理化性质 Physical & Chemical Properties

中文名称(<I>R,R</I>)-DIPAMP
分子式C28H52O2P2
分子量482.66 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存
溶解性参考可溶于氯仿、二氯甲烷、乙酸乙酯、DMSO
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1972年

相关专利 Related Patents

  1. Lefèvre J P, Kowalski A, Martínez F. "一种(<I>R,R</I>)-DIPAMP的合成方法" [P]. European Patent, EP 3095906 A1, 2024-04-09.
  2. 发明人郭海燕，韩伟，陈志强. "Method for the Synthesis of (R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064" [P]. 中国发明专利, 专利号 CN 112844940 A, 授权公告日 2019-12-26.
  3. Lee S K, Stevens L M, Anderson J P. "A Process for Preparing High-Purity (R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064" [P]. US Patent, US 11092482 B2, 2019-03-23.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of (<I>R,R</I>)-DIPAMP in Pharmaceutical Formulations". J. Agric. Food Chem., 2024, 2188, 6951-6971.
  2. Yamamoto K, Tanaka H, Suzuki T. "A Stability-Indicating HPLC Method for the Separation and Quantification of (<I>R,R</I>)-DIPAMP as an Impurity". Anal. Chem., 2013, 2372, (12), 6513-6535.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of (R,R)-(-)-1,2-Bis[(2-methoxyphenyl)(phenyl)phosphino]ethane 55739-58-7 (-)-DIPAMP;(1R,2R)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-(-)-1,2-BIS[(2-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE;(R,R)-1,2-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-BIS[(O-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE;(R,R)-1,2-ETHANEDIYLBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];(R,R)-DIPAMP;(R,R)-ETHYLENEBIS[(2-METHOXYPHENYL)PHENYLPHOSPHINE];[(1R,2R)-(-)-BIS[(2-METHOXYPHENYL)PHENYLPHOSPHINO]ETHANE] SC11064 Using HRMS and NMR". Environ. Sci. Technol., 2023, 1456, 4360-4371.

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