12:0 PE CAS 59752-57-7

1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(12:0/12:0)

纯度 97%+现货药物标准品
CAS 号59752-57-7
分子式C29H58NO8P
分子量579.75 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

12:0 PE 1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(12:0/12:0) CAS 59752-57-7 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品12:0 PE（1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(12:0/12:0)，CAS 59752-57-7），分子式 C29H58NO8P，分子量 579.75。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

从化学结构特征来看，12:0 PE的分子骨架中包含酰胺类，含磷酸酯基，羧酸类，含羟基，含醚键。该化合物的不饱和度为1.5，表明结构中存在约1个环或双键等价单元。分子量为579.75 g/mol，属于较高分子量化合物。含氮官能团的存在使该化合物在ESI正离子模式下具有优良的离子化效率，适合LC-MS/MS分析。 化学式为 C29H58NO8P 的12:0 PE（1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-(2-aminoethoxy)hydroxyphosphinyloxymethyl-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(

应用场景：12:0 PE（1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1- (2-aminoethoxy)hydroxyphosphinyl oxy methyl -1,2-ethanediyl ester L-|A,|A

理化性质 Physical & Chemical Properties

中文名称12:0 PE
分子式C29H58NO8P
分子量579.75 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，避光，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）1.5
CAS登记年份（估）1974年
含氮原子数1

相关专利 Related Patents

  1. 发明人郑宇鹏，罗永刚，林芳. "一种12:0 PE的合成方法" [P]. 中国发明专利, 专利号 CN 115792884 A, 授权公告日 2022-07-27.
  2. Patel M V, Stevens L M, Yamamoto T. "Method for the Synthesis of 1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(12:0/12:0)" [P]. US Patent, US 10324857 B2, 2025-06-14.

参考文献 Literature

  1. Wang L, Li J, Zhang H. "Development and Validation of an LC-MS/MS Method for the Determination of 12:0 PE in Pharmaceutical Formulations". Anal. Methods, 2018, 1413, (6), 3033-3042.
  2. Wang L, Li J, Zhang H. "A Stability-Indicating HPLC Method for the Separation and Quantification of 12:0 PE as an Impurity". Phytochemistry, 2010, 1314, 1440-1451.

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