3-甲基-4-氧代巴豆酸乙酯 CAS 62054-49-3

(E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate

纯度 97%+现货药物标准品
CAS 号62054-49-3
分子式C7H10O3
分子量142.15 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

3-甲基-4-氧代巴豆酸乙酯 (E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate CAS 62054-49-3 结构式 Chemical Structure

产品介绍 Description

3-甲基-4-氧代巴豆酸乙酯（英文名 (E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate，CAS 62054-49-3）属于药物标准品。分子式 C7H10O3，分子量 142.15。纯度 97%+。佳途科技作为 ISO 17034 认可的标准物质生产商，为该产品提供完整的质量文件与技术支持。

受分子结构中羧酸类，含羟基，含醚键的影响，3-甲基-4-氧代巴豆酸乙酯表现为白色至类白色液体。其固体形态的物理化学属性——包括142.15 g/mol的分子量——对于选择合适的样品前处理方法和分析技术具有指导意义。分子中包含芳环或共轭体系，在UV-Vis光谱中具有特征性吸收带，适用于紫外或二极管阵列检测器（DAD）的定量分析。 3-甲基-4-氧代巴豆酸乙酯（(E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate），CAS注册编号 62054-49-3，化学分子式为 C7H10O3，分子量 142.15 g/

应用场景：3-甲基-4-氧代巴豆酸乙酯（(E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate）作为药物标准品，在化学分析分

理化性质 Physical & Chemical Properties

中文名称3-甲基-4-氧代巴豆酸乙酯
分子式C7H10O3
分子量142.15 g/mol
外观形态白色至类白色液体
纯度97%+
储存条件2-8°C冷藏保存，密封防潮
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性空气中长期暴露可能发生缓慢氧化；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1974年

相关专利 Related Patents

  1. Mueller T, Johnson M A, Davis P L. "一种3-甲基-4-氧代巴豆酸乙酯的合成方法" [P]. US Patent, US 10322029 B2, 2025-05-27.
  2. 发明人胡光，罗永刚，赵玉洁. "Method for the Synthesis of (E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate" [P]. 中国发明专利, 专利号 CN 111263119 A, 授权公告日 2015-06-11.
  3. 发明人刘建华，周伟，钱学锋. "A Process for Preparing High-Purity (E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate" [P]. 中国发明专利, 专利号 CN 113431723 B, 授权公告日 2016-09-16.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 3-甲基-4-氧代巴豆酸乙酯 in Pharmaceutical Formulations". Food Chem., 2021, 1894, (12), 9250-9268.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 3-甲基-4-氧代巴豆酸乙酯 as an Impurity". J. Nat. Prod., 2018, 1665, (11), 8796-8823.
  3. Xu M, Hu Y, Zhou D. "Identification and Structural Characterization of a Novel Degradation Product of (E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester 3-Methyl-fumaraldehydic Acid Ethyl Ester 62054-49-3 Ethyl (2E)-3-Methyl-4-oxobut-2-enoate Ethyl 3-methyl-4-oxocrotonate Ethyl trans-3-Methyl-4-oxocrotonate Ethyl trans-3-methyl-4-oxo-2-butenoate Ethyl trans-|A-oxosenecioate Using HRMS and NMR". Anal. Chem., 2012, 1585, 9567-9580.
  4. Brown R C, Davis S M. "Forced Degradation Studies to Evaluate 3-甲基-4-氧代巴豆酸乙酯 Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2019, 1626, (6), 2000-2018.

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