四甲基溴化铵 CAS 64-20-0

6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P

纯度 97%+现货药物标准品
CAS 号64-20-0
分子式Br C4H12N
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

四甲基溴化铵 6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P CAS 64-20-0 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品四甲基溴化铵（6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P，CAS 64-20-0），分子式 Br C4H12N。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

推荐用于分析方法开发与验证，产品提供完整COA证书，确保ISO 17034标准的量值溯源要求。适用于GLP实验室的日常分析。 四甲基溴化铵（6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P），CAS注册编号 64-20-0，化学分子式为 Br C4H12N，分子量 154.05 g/mol。 受分子结构中含溴取代的影响，四甲基溴化铵表现为白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）。其固体形态的物理化学属性——包

应用场景：针对化学分析用途，四甲基溴化铵（6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L

理化性质 Physical & Chemical Properties

中文名称四甲基溴化铵
分子式Br C4H12N
分子量154.05 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密闭保存防止挥发
溶解性参考可溶于甲醇、乙腈、DMSO
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）-1.0
CAS登记年份（估）1957年
卤素含量Br取代
含氮原子数1

相关专利 Related Patents

  1. Björnsson E, Kowalski A, Lefèvre J P. "一种四甲基溴化铵的合成方法" [P]. European Patent, EP 3184205 A1, 2020-01-24.
  2. 发明人刘建华，钱学锋，黄志刚. "Method for the Synthesis of 6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P" [P]. 中国发明专利, 专利号 CN 117599836 A, 授权公告日 2017-11-26.

参考文献 Literature

  1. Xu M, Hu Y, Zhou D. "Development and Validation of an LC-MS/MS Method for the Determination of 四甲基溴化铵 in Pharmaceutical Formulations". Chemosphere, 2012, 2177, (7), 538-555.
  2. Zhou X P, Huang L, Wu G. "A Stability-Indicating HPLC Method for the Separation and Quantification of 四甲基溴化铵 as an Impurity". J. Chromatogr. A, 2023, 628, (4), 2541-2553.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 6L9NE9609P 64-20-0 Tetramethylammonium bromide Ammonium, tetramethyl-, bromide Methanaminium, N,N,N-trimethyl-, bromide Methyl, (dimethylamino)-, methobromide (7CI) Methanaminium, N,N,N-trimethyl-, bromide (1:1) EINECS 200-581-2 NSC 148344 N,N,N-Trimethylmethanaminium bromide UNII-6L9NE9609P Using HRMS and NMR". Anal. Methods, 2019, 1119, (1), 8998-9012.
  4. Hughes D, Roberts J, Thomas A. "Forced Degradation Studies to Evaluate 四甲基溴化铵 Profile in Drug Substances According to ICH Guidelines". Anal. Chim. Acta, 2020, 433, 3728-3758.

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