次氮基三亚甲基膦酸 CAS 6419-19-8
1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(methylenephosphonic acid) Aminotri(methylphosphonic acid) Aminotris(methanephosphonic acid) Aminotris(methylphosphonic acid) BRN 1715724 Dequest 2000 Dowell L 37 EINECS 229-146-5 Ferrofos 509 Nitrilotrimethanephosphonic acid Nitrilotrimethylenephosphonic acid Nitrilotrimethylphosphonic acid (Nitrilotris(methylene))trisphosphonic acid Nitrilotris(methylphosphonic acid) Tris(phosphonomethyl)amine UNII-1Y702GD0FG EC 229-146-5 Nitrilotris(methylenephosphonic acid) Phosphoric acid, (nitrilotris-(methylene))tris-
| CAS 号 | 6419-19-8 |
| 分子式 | C3H12NO9P3 |
| 分子量 | 299.05 g/mol |
| 分类 | 药物标准品 / 原料药标准品 |
| 库存状态 | 现货 |
化学结构式 Structure
产品介绍 Description
CAS 6419-19-8 对应的次氮基三亚甲基膦酸（1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(methylenephosphonic acid) Aminotri(methylphosphonic acid) Aminotris(methanephosphonic acid) Aminotris(methylphosphonic acid) BRN 1715724 Dequest 2000 Dowell L 37 EINECS 229-146-5 Ferrofos 509 Nitrilotrimethanephosphonic acid Nitrilotrimethylenephosphonic acid Nitrilotrimethylphosphonic acid (Nitrilotris(methylene))trisphosphonic acid Nitrilotris(methylphosphonic acid) Tris(phosphonomethyl)amine UNII-1Y702GD0FG EC 229-146-5 Nitrilotris(methylenephosphonic acid) Phosphoric acid, (nitrilotris-(methylene))tris-）为 CATO 佳途药物标准品产品线成员。分子式 C3H12NO9P3，分子量 299.05。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认，质量稳定可溯源。
化学式为 C3H12NO9P3 的次氮基三亚甲基膦酸（1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(meth
应用场景：针对化学分析用途，次氮基三亚甲基膦酸（1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phospho
理化性质 Physical & Chemical Properties
| 中文名称 | 次氮基三亚甲基膦酸 |
| 分子式 | C3H12NO9P3 |
| 分子量 | 299.05 g/mol |
| 外观形态 | 白色至类白色结晶性粉末。（具有氨/胺类微弱气味） |
| 纯度 | 97%+ |
| 储存条件 | 2-8°C冷藏保存，避光，密封防潮 |
| 溶解性参考 | 可溶于甲醇、乙醇、DMSO、水 |
| 稳定性 | 对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封 |
| 化合物类型 | 药物标准品 |
| 子类 | 原料药标准品 |
| 不饱和度（DBE） | -1.5 |
| CAS登记年份（估） | 1958年 |
| 含氮原子数 | 1 |
相关专利 Related Patents
- 发明人李文辉，韩伟，朱建伟. "一种次氮基三亚甲基膦酸的合成方法" [P]. 中国发明专利, 专利号 CN 114245153 A, 授权公告日 2021-10-07.
- 发明人李文辉，徐明华，高志强. "Method for the Synthesis of 1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(methylenephosphonic acid) Aminotri(methylphosphonic acid) Aminotris(methanephosphonic acid) Aminotris(methylphosphonic acid) BRN 1715724 Dequest 2000 Dowell L 37 EINECS 229-146-5 Ferrofos 509 Nitrilotrimethanephosphonic acid Nitrilotrimethylenephosphonic acid Nitrilotrimethylphosphonic acid (Nitrilotris(methylene))trisphosphonic acid Nitrilotris(methylphosphonic acid) Tris(phosphonomethyl)amine UNII-1Y702GD0FG EC 229-146-5 Nitrilotris(methylenephosphonic acid) Phosphoric acid, (nitrilotris-(methylene))tris-" [P]. 中国发明专利, 专利号 CN 109659989 A, 授权公告日 2024-10-11.
- 发明人孙丽萍，周伟，沈红梅. "A Process for Preparing High-Purity 1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(methylenephosphonic acid) Aminotri(methylphosphonic acid) Aminotris(methanephosphonic acid) Aminotris(methylphosphonic acid) BRN 1715724 Dequest 2000 Dowell L 37 EINECS 229-146-5 Ferrofos 509 Nitrilotrimethanephosphonic acid Nitrilotrimethylenephosphonic acid Nitrilotrimethylphosphonic acid (Nitrilotris(methylene))trisphosphonic acid Nitrilotris(methylphosphonic acid) Tris(phosphonomethyl)amine UNII-1Y702GD0FG EC 229-146-5 Nitrilotris(methylenephosphonic acid) Phosphoric acid, (nitrilotris-(methylene))tris-" [P]. 中国发明专利, 专利号 CN 111966679 B, 授权公告日 2018-07-03.
参考文献 Literature
- Smith J A, Johnson M B. "Development and Validation of an LC-MS/MS Method for the Determination of 次氮基三亚甲基膦酸 in Pharmaceutical Formulations". J. Agric. Food Chem., 2024, 746, (6), 5569-5575.
- Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of 次氮基三亚甲基膦酸 as an Impurity". Talanta, 2017, 1407, 4487-4516.
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