4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline CAS 6523-49-5

1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline

纯度 97%+现货药物标准品
CAS 号6523-49-5
分子式C8H18N4
分子量170.26 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline 1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline CAS 6523-49-5 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline（1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline）为药物标准品，CAS 登记号 6523-49-5，分子式 C8H18N4，分子量 170.26。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline的产生途径与其化学式中含氰基密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline（1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-1,2,4triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline），CAS注册编号 6523-49-5，化学分子式为 C8H18N4，分子量 170.26 g/mol。 4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline（C8H18N4）含有含氰基。其物理化学性质在同类化合物中具有代表性，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。分子中的氮原子赋予该化

应用场景：4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline（1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4- 1,2,4 triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline，CAS 6523-49-5）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以4-(1<I>H</I>-1,2

理化性质 Physical & Chemical Properties

中文名称4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline
分子式C8H18N4
分子量170.26 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1958年
含氮原子数4

相关专利 Related Patents

  1. Nowak P, Kowalski A, Mueller T C. "一种4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline的合成方法" [P]. European Patent, EP 3527559 A1, 2022-09-15.
  2. 发明人沈红梅，马晓峰，徐明华. "Method for the Synthesis of 1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline" [P]. 中国发明专利, 专利号 CN 112513260 A, 授权公告日 2017-01-07.
  3. 发明人陈志强，钱学锋，马晓峰. "A Process for Preparing High-Purity 1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline" [P]. 中国发明专利, 专利号 CN 116739739 A, 授权公告日 2019-04-20.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of 4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline in Pharmaceutical Formulations". Anal. Chim. Acta, 2018, 2433, (8), 2092-2095.
  2. O'Brien K, Kennedy M L. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline as an Impurity". Sci. Total Environ., 2025, 1234, (10), 1327-1340.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 1-(4'-Aminophenyl)-1,2,4-triazole 1-(4-aminophenyl)-1,2,4-triazole 4-(1h-1,2,4-triazol-1-yl)aniline 4-[1,2,4]triazol-1-yl-phenylamine 6523-49-5 benzenamine, 4-(1h-1,2,4-triazol-1-yl)- triazolylaniline Using HRMS and NMR". Anal. Chem., 2019, 1341, (10), 2315-2335.
  4. Zhou X P, Huang L, Wu G. "Forced Degradation Studies to Evaluate 4-(1<I>H</I>-1,2,4-Triazol-1-yl)aniline Profile in Drug Substances According to ICH Guidelines". J. Nat. Prod., 2020, 369, 8492-8521.

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