5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide CAS 676500-67-7

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide

纯度 97%+现货药物标准品
CAS 号676500-67-7
分子式C20H26N4O4
分子量386.44 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide CAS 676500-67-7 结构式 Chemical Structure

产品介绍 Description

本产品为药物标准品5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide（5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide，CAS 676500-67-7），分子式 C20H26N4O4，分子量 386.44。纯度 97%+。适用于分析方法开发、方法验证及日常质检，CATO 提供全程冷链与全球配送。

与同类药物标准品相比，5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide的分子量为386.44 g/mol这一特征使其在色谱分离条件和质谱检测参数设置上具有独特性。 化学式为 C20H26N4O4 的5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide（5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide），其CAS登记号是 676500-67-7，分子量为 386.44 g/mol。 受分子结构中黄酮骨架，酰胺类，含羟基，含醚键的影响，5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phen

应用场景：5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide（5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide，CAS 676500-67-7）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methy

理化性质 Physical & Chemical Properties

中文名称5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide
分子式C20H26N4O4
分子量386.44 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1985年
含氮原子数4

相关专利 Related Patents

  1. 发明人杨光，罗永刚，林芳. "一种5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide的合成方法" [P]. 中国发明专利, 专利号 CN 109940427 B, 授权公告日 2024-09-19.
  2. Johnson M A, Kumar R, Schröder R. "Method for the Synthesis of 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide" [P]. US Patent, US 11799988 B2, 2021-11-24.

参考文献 Literature

  1. Fischer P, Wagner E. "Development and Validation of an LC-MS/MS Method for the Determination of 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2015, 2377, 2787-2801.
  2. Kowalski T, Nowak Z. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide as an Impurity". Environ. Sci. Technol., 2020, 1512, (6), 8146-8157.
  3. Zhou X P, Huang L, Wu G. "Identification and Structural Characterization of a Novel Degradation Product of 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide Using HRMS and NMR". J. Agric. Food Chem., 2010, 1576, 2609-2626.

Related Methoxy Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...