4,9-二噁-1,12-十二烷二胺 CAS 7300-34-7

7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9-dioxadodecane alpha,omega-Diamino-4,9-dioxadodecane EINECS 230-745-9 NSC 36635 Propylamine, 3,3'-(tetramethylenedioxy)bis- 3,3'-(Tetramethylenedioxy)bis(propylamine) EC 230-745-9

纯度 97%+现货药物标准品
CAS 号7300-34-7
分子式C10H24N2O2
分子量204.31 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4,9-二噁-1,12-十二烷二胺 7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9-dioxadodecane alpha,omega-Diamino-4,9-dioxadodecane EINECS 230-745-9 NSC 36635 Propylamine, 3,3'-(tetramethylenedioxy)bis- 3,3'-(Tetramethylenedioxy)bis(propylamine) EC 230-745-9 CAS 7300-34-7 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的4,9-二噁-1,12-十二烷二胺（7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9-dioxadodecane alpha,omega-Diamino-4,9-dioxadodecane EINECS 230-745-9 NSC 36635 Propylamine, 3,3'-(tetramethylenedioxy)bis- 3,3'-(Tetramethylenedioxy)bis(propylamine) EC 230-745-9）为药物标准品，CAS 登记号 7300-34-7，分子式 C10H24N2O2，分子量 204.31。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

4,9-二噁-1,12-十二烷二胺（C10H24N2O2）含有氨基酸衍生物，酰胺类，含羟基，含醚键。具有较强的吸湿性，较高的碳氢比使其脂溶性较好，羧基赋予其一定的酸性特征，这些物理化学性质直接决定了其标准溶液的最佳配制方案和储存策略。分子中的氮原子赋予该化合物一定的碱性特征，在酸性流动相条件下可被有效质子化。 CAS编号 7300-34-7 对应的化合物4,9-二噁-1,12-十二烷二胺（英文标识 7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9

应用场景：4,9-二噁-1,12-十二烷二胺（7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether

理化性质 Physical & Chemical Properties

中文名称4,9-二噁-1,12-十二烷二胺
分子式C10H24N2O2
分子量204.31 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）0.0
CAS登记年份（估）1959年
含氮原子数2

相关专利 Related Patents

  1. 发明人王建平，钱学锋，孙丽萍. "一种4,9-二噁-1,12-十二烷二胺的合成方法" [P]. 中国发明专利, 专利号 CN 108622719 B, 授权公告日 2015-10-05.
  2. Kowalski A, Nielsen H, Sørensen M. "Method for the Synthesis of 7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9-dioxadodecane alpha,omega-Diamino-4,9-dioxadodecane EINECS 230-745-9 NSC 36635 Propylamine, 3,3'-(tetramethylenedioxy)bis- 3,3'-(Tetramethylenedioxy)bis(propylamine) EC 230-745-9" [P]. European Patent, EP 3737907 A1, 2024-10-17.

参考文献 Literature

  1. Yang F, Sun W, Liu J. "Development and Validation of an LC-MS/MS Method for the Determination of 4,9-二噁-1,12-十二烷二胺 in Pharmaceutical Formulations". Food Chem., 2015, 2300, (8), 308-328.
  2. Fischer P, Wagner E. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4,9-二噁-1,12-十二烷二胺 as an Impurity". J. Chromatogr. A, 2020, 681, 2091-2113.
  3. Lee J H, Choi Y S. "Identification and Structural Characterization of a Novel Degradation Product of 7300-34-7 4,9-Dioxa-1,12-dodecanediamine 3,3'-(Butane-1,4-diylbis(oxy))bispropanamine 1-Propanamine, 3,3'-(1,4-butanediylbis(oxy))bis- 1,4-Bis(gamma-aminopropoxy)butane 1,4-Bis(3-aminopropoxy)butane 1,4-Butanediol bis(gamma-aminopropyl) ether 1,4-Butanediol bis(3-aminopropyl)ether 1,12-Diamino-4,9-dioxadodecane alpha,omega-Diamino-4,9-dioxadodecane EINECS 230-745-9 NSC 36635 Propylamine, 3,3'-(tetramethylenedioxy)bis- 3,3'-(Tetramethylenedioxy)bis(propylamine) EC 230-745-9 Using HRMS and NMR". J. Agric. Food Chem., 2015, 1602, 9623-9643.
  4. Zhang Y, Li Q, Chen T. "Forced Degradation Studies to Evaluate 4,9-二噁-1,12-十二烷二胺 Profile in Drug Substances According to ICH Guidelines". Talanta, 2015, 1380, 6387-6397.

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