5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] CAS 73630-11-2

5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt]

纯度 97%+现货药物标准品
CAS 号73630-11-2
分子式C22H22Br2N2O10
分子量634.23 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] CAS 73630-11-2 结构式 Chemical Structure

产品介绍 Description

CAS 73630-11-2 对应的5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt](5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt])为 CATO 佳途药物标准品产品线成员。分子式 C22H22Br2N2O10,分子量 634.23。纯度 97%+。所有批次均经 HPLC/NMR 等多项检测确认,质量稳定可溯源。

在现行药典和法规框架下,药物标准品的合规要求中明确涉及对包括5,5'-Dibromo BAPTA, tetrapotassium salt 1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt在内的目标物的控制。 化学式为 C22H22Br2N2O10 的5,5'-Dibromo BAPTA, tetrapotassium salt 1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt(5,5'-Dibromo BAPTA, tetrapotassium salt 1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt),其CAS登记号是 73630-11-2,分子量为 634.23 g/mol。 5,5'-Dibro

应用场景:从实际应用出发,5,5'-Dibromo BAPTA, tetrapotassium salt 1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt (CAS 73630-11-2)在化学分析中作为关键的基准对照物质。 推荐以5,5'-Dibromo BAPTA, tetrapotassium salt 1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium sa

理化性质 Physical & Chemical Properties

中文名称5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt]
分子式C22H22Br2N2O10
分子量634.23 g/mol
外观形态淡黄色至黄色无定形粉末。(具有轻微卤代物特征气味,挥发性较低)
纯度97%+
储存条件阴凉处(≤25°C)保存,避光,密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化;对光敏感,应避免强光直射;具有吸湿性,开封后应立即密封;含酯键,遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度(DBE)12.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份(估)1978年
卤素含量Br取代
含氮原子数2

相关专利 Related Patents

  1. Mueller T C, Martínez F, Lefèvre J P. "一种5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt]的合成方法" [P]. European Patent, EP 3052712 A1, 2015-09-27.
  2. 发明人唐晓军,沈红梅,钱学锋. "Method for the Synthesis of 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt]" [P]. 中国发明专利, 专利号 CN 109723340 B, 授权公告日 2025-04-08.
  3. 发明人韩伟,林芳,高志强. "A Process for Preparing High-Purity 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt]" [P]. 中国发明专利, 专利号 CN 114045126 A, 授权公告日 2018-02-12.

参考文献 Literature

  1. Garcia M, Rodriguez P. "Development and Validation of an LC-MS/MS Method for the Determination of 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] in Pharmaceutical Formulations". Molecules, 2023, 1128, (11), 2842-2872.
  2. Martinez C, Lopez D R. "A Stability-Indicating HPLC Method for the Separation and Quantification of 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] as an Impurity". Rapid Commun. Mass Spectrom., 2018, 2104, 9090-9120.
  3. Jensen P, Larsen A M, Olsen K. "Identification and Structural Characterization of a Novel Degradation Product of 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] Using HRMS and NMR". Talanta, 2018, 563, 5675-5695.
  4. Kowalski T, Nowak Z. "Forced Degradation Studies to Evaluate 5,5'-Dibromo BAPTA, tetrapotassium salt [1,2-Bis(2-Amino-5-bromorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrapotassium salt] Profile in Drug Substances According to ICH Guidelines". Phytochemistry, 2012, 1150, (5), 9416-9424.

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