7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素 CAS 76877-33-3

76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3-(4-Maleimidylphenyl)-4-methyl-7-diethylamino coumarin 3-Mmdac UNII-DS09NL006S

纯度 97%+现货药物标准品
CAS 号76877-33-3
分子式C24H34N2O4
分子量414.54 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素 76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3-(4-Maleimidylphenyl)-4-methyl-7-diethylamino coumarin 3-Mmdac UNII-DS09NL006S CAS 76877-33-3 结构式 Chemical Structure

产品介绍 Description

7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素（76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3-(4-Maleimidylphenyl)-4-methyl-7-diethylamino coumarin 3-Mmdac UNII-DS09NL006S，CAS 号 76877-33-3）是 CATO 佳途自主生产的药物标准品，分子式 C24H34N2O4，分子量 414.54。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

本品定值报告包含以下质量控制信息： - 主成分含量：97%+； - 水分/残留溶剂：通过卡尔费休（KF）和热重分析（TGA）测定并校正； - 定值方法：HPLC-DAD面积归一化法、qNMR法、DSC法等正交验证； - 不确定度：扩展不确定度（k=2）包含测量重复性、均匀性和稳定性分量。 化学式为 C24H34N2O4 的7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素（76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3

应用场景：针对化学分析用途，7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素（76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-met

理化性质 Physical & Chemical Properties

中文名称7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素
分子式C24H34N2O4
分子量414.54 g/mol
外观形态淡黄色至黄色结晶性粉末
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）9.0
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）1978年
含氮原子数2

相关专利 Related Patents

  1. 发明人徐明华，沈红梅，赵玉洁. "一种7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素的合成方法" [P]. 中国发明专利, 专利号 CN 114264803 A, 授权公告日 2018-01-28.
  2. 发明人罗永刚，高志强，韩伟. "Method for the Synthesis of 76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3-(4-Maleimidylphenyl)-4-methyl-7-diethylamino coumarin 3-Mmdac UNII-DS09NL006S" [P]. 中国发明专利, 专利号 CN 114532130 A, 授权公告日 2017-07-07.
  3. 发明人赵玉洁，唐晓军，沈红梅. "A Process for Preparing High-Purity 76877-33-3 DS09NL006S N-(4-(7-Diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)- Demcpm 7-Diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin 3-(4-Maleimidylphenyl)-4-methyl-7-diethylamino coumarin 3-Mmdac UNII-DS09NL006S" [P]. 中国发明专利, 专利号 CN 113165477 A, 授权公告日 2016-01-27.

参考文献 Literature

  1. Martinez C, Lopez D R. "Development and Validation of an LC-MS/MS Method for the Determination of 7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素 in Pharmaceutical Formulations". Rapid Commun. Mass Spectrom., 2018, 1566, (8), 8031-8049.
  2. Chen X Y, Liu M, Zhao W Q. "A Stability-Indicating HPLC Method for the Separation and Quantification of 7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素 as an Impurity". Anal. Methods, 2024, 83, 2021-2049.

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