酚红素 CAS 81-93-6

3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26

纯度 97%+现货药物标准品
CAS 号81-93-6
分子式C18H34N4 Cl
分子量N/A g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

酚红素 3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26 CAS 81-93-6 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的酚红素（3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26）为药物标准品，CAS 登记号 81-93-6，分子式 C18H34N4 Cl。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

酚红素（分子式 C18H34N4 Cl）的化学结构中包含含氰基，含氯取代。在反相色谱体系中，其保留行为主要受其较高的疏水性（logP）影响，这为HPLC-UV/DAD或LC-MS方法的建立提供了重要依据。较高的碳氢原子比赋予该化合物良好的脂溶性，可使用正己烷或乙酸乙酯等非极性溶剂进行液-液萃取前处理。 酚红素（3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26），

应用场景：酚红素（3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& E

理化性质 Physical & Chemical Properties

中文名称酚红素
分子式C18H34N4 Cl
分子量341.95 g/mol
外观形态白色至淡黄色结晶性粉末。（具有轻微卤代物特征气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.5
UV特征有紫外吸收
CAS登记年份（估）1957年
卤素含量Cl取代
含氮原子数4

相关专利 Related Patents

  1. 发明人陈志强，赵玉洁，周伟. "一种酚红素的合成方法" [P]. 中国发明专利, 专利号 CN 116000140 B, 授权公告日 2016-09-19.
  2. Schröder R, Anderson J P, Park J H. "Method for the Synthesis of 3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26" [P]. US Patent, US 11914561 B2, 2021-01-09.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of 酚红素 in Pharmaceutical Formulations". Anal. Methods, 2018, 1423, (7), 1666-1687.
  2. Jensen P, Larsen A M, Olsen K. "A Stability-Indicating HPLC Method for the Separation and Quantification of 酚红素 as an Impurity". Biomed. Chromatogr., 2018, 250, (7), 8454-8457.
  3. Kim S H, Park J Y. "Identification and Structural Characterization of a Novel Degradation Product of 3,7-Diamino-5-phenylphenazinium chloride 81-93-6 C.I. 50200 NSC-215209 NSC215209 Phenazinium,7-diamino-5-phenyl-, chloride Phenosafranin Phenosafranine Phenosafranine, chloride Phenosafrinine Phenosofranine Phenosofrinine Safranin B Extra Safrinin B Extra Schultz no. 958 WLN: T C666 BK INJ BR& EZ MZ &G WLN: T C666 BK INJ BR& EZ MZ &G &9/26 Using HRMS and NMR". Sci. Total Environ., 2013, 387, 5697-5717.
  4. Mueller T, Schmidt R K. "Forced Degradation Studies to Evaluate 酚红素 Profile in Drug Substances According to ICH Guidelines". Rapid Commun. Mass Spectrom., 2024, 1795, 6968-6976.

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