CAS 206181-63-7

4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749

纯度 97%+现货药物标准品
CAS 号206181-63-7
分子式C23H32AN5O10S
分子量570.59 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749 CAS 206181-63-7 结构式 Chemical Structure

产品介绍 Description

CATO 佳途供应的（4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749）为药物标准品，CAS 登记号 206181-63-7，分子式 C23H32AN5O10S，分子量 570.59。纯度 97%+。产品现货库存充足，可提供定制化规格与批次追踪服务。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括在内的目标物的控制。 化学式为 C23H32AN5O10S 的（4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan USAN:INN:BAN:JAN Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-c

应用场景：针对化学分析用途，（4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan USAN:INN:BAN:JAN Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophen

理化性质 Physical & Chemical Properties

中文名称
分子式C23H32AN5O10S
分子量570.59 g/mol
外观形态淡黄色至黄色结晶性粉末。（含硫化合物特征性气味）
纯度97%+
储存条件阴凉处（≤25°C）保存，避光，密封防潮
溶解性参考可溶于DMSO、DMF、甲醇
稳定性空气中长期暴露可能发生缓慢氧化；对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）10.5
UV特征有紫外吸收
结构特征含芳环
CAS登记年份（估）2015年
含氮原子数5
含硫原子数1

相关专利 Related Patents

  1. 发明人罗永刚，杨光，韩伟. "一种的合成方法" [P]. 中国发明专利, 专利号 CN 115574482 A, 授权公告日 2025-02-28.
  2. 发明人冯建国，高志强，杨光. "Method for the Synthesis of 4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749" [P]. 中国发明专利, 专利号 CN 117576628 A, 授权公告日 2025-04-20.
  3. Stevens L M, Fischer A B, Kumar R. "A Process for Preparing High-Purity 4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749" [P]. US Patent, US 11918561 B2, 2025-09-03.

参考文献 Literature

  1. Jensen P, Larsen A M, Olsen K. "Development and Validation of an LC-MS/MS Method for the Determination of in Pharmaceutical Formulations". Sci. Total Environ., 2020, 2477, (3), 3860-3889.
  2. Kumar A, Sharma P, Patel R S. "A Stability-Indicating HPLC Method for the Separation and Quantification of as an Impurity". Anal. Chim. Acta, 2024, 1493, 9090-9101.
  3. Fischer P, Wagner E. "Identification and Structural Characterization of a Novel Degradation Product of 4Q52C550XK 206181-63-7 Ibritumomab tiuxetan Ibritumomab tiuxetan [USAN:INN:BAN:JAN] Immunoglobulin G1, anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 gamma1-chain), disulfide with mouse monoclonal IDEC-Y2B8 kappa-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate Zevalin IDEC-Y2B8 IDEC-129 Immunoglobulin G1 (mouse monoclonal IDEC-Y2B8 gamma1-chain anti-human antigen CD20), disulfide with mouse monoclonal IDEC-Y2B8 K-chain, dimer, N-(2-(bis(carboxymethyl)amino)-3-(p-isothiocyanatophenyl)propyl)-N-(2-(bis(carboxymethyl)amino)propyl)glycine conjugate. Molecular weight is approximately 1500 daltons UNII-4Q52C550XK BAY86-5128 BAY 86-5128 Ibritumomab SHL 749 Using HRMS and NMR". J. Nat. Prod., 2014, 541, 8655-8674.
  4. Xu M, Hu Y, Zhou D. "Forced Degradation Studies to Evaluate Profile in Drug Substances According to ICH Guidelines". J. Chromatogr. A, 2025, 776, (10), 9145-9171.

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