piperazine-1-carboxylic acid dimethylamide CAS 41340-78-7

Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7

纯度 97%+现货药物标准品
CAS 号41340-78-7
分子式C7H15N3O
分子量157.21 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

piperazine-1-carboxylic acid dimethylamide Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7 CAS 41340-78-7 结构式 Chemical Structure

产品介绍 Description

piperazine-1-carboxylic acid dimethylamide（Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7，CAS 号 41340-78-7）是 CATO 佳途自主生产的药物标准品，分子式 C7H15N3O，分子量 157.21。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

piperazine-1-carboxylic acid dimethylamide的产生途径与其化学式中酰胺类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 CAS编号 41340-78-7 对应的化合物piperazine-1-carboxylic acid dimethylamide（英文标识 Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7），化学式 C7H15N3O，相对分子质量 157.21。 piperazine-1-carboxylic acid dimethylamide（C7H15N3O）含有酰胺类，含羟基，含醚键。其物理化学性质在同类化合物中具有代表性，这些物理化学性质直接决定了其标准溶液的最

应用场景：piperazine-1-carboxylic acid dimethylamide（Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7，CAS 41340-78-7）的标准化应用场景涵盖化学分析等多个专业技术领域。 推荐以piperazine-1-carboxyl

理化性质 Physical & Chemical Properties

中文名称piperazine-1-carboxylic acid dimethylamide
分子式C7H15N3O
分子量157.21 g/mol
外观形态白色至类白色结晶性粉末。（具有氨/胺类微弱气味）
纯度97%+
储存条件2-8°C冷藏保存，避光
溶解性参考可溶于DMSO、DMF、甲醇
稳定性对光敏感，应避免强光直射
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1968年
含氮原子数3

相关专利 Related Patents

  1. Nielsen H, Mueller T C, Jørgensen K. "一种piperazine-1-carboxylic acid dimethylamide的合成方法" [P]. European Patent, EP 3444507 A1, 2015-04-03.
  2. Sørensen M, Kowalski A, Mueller T C. "Method for the Synthesis of Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7" [P]. European Patent, EP 3771028 A1, 2017-10-01.
  3. O'Brien P Q, Davis P L, Patel M V. "A Process for Preparing High-Purity Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7" [P]. US Patent, US 11829080 B2, 2019-05-03.

参考文献 Literature

  1. Kim S H, Park J Y. "Development and Validation of an LC-MS/MS Method for the Determination of piperazine-1-carboxylic acid dimethylamide in Pharmaceutical Formulations". J. Pharm. Biomed. Anal., 2019, 2401, (3), 7404-7422.
  2. Lee J H, Choi Y S. "A Stability-Indicating HPLC Method for the Separation and Quantification of piperazine-1-carboxylic acid dimethylamide as an Impurity". Talanta, 2018, 1192, (9), 7202-7216.
  3. Wang L, Li J, Zhang H. "Identification and Structural Characterization of a Novel Degradation Product of Piperazine-1-carboxylic acid dimethylamide n,n-dimethylpiperazine-1-carboxamide n'-1',n'-1'-dimethyltetrahydro-1(2h)-pyrazinecarboxamide piperazine-1-carboxylic acid dimethyl amide 41340-78-7 Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2022, 1013, (2), 3773-3797.
  4. Smith J A, Johnson M B. "Forced Degradation Studies to Evaluate piperazine-1-carboxylic acid dimethylamide Profile in Drug Substances According to ICH Guidelines". Biomed. Chromatogr., 2017, 1909, (7), 7025-7034.

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