4-fluoro-3-nitrophenyl methyl sulfone CAS 453-72-5

4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5

纯度 97%+现货药物标准品
CAS 号453-72-5
分子式C7H12FNO4S
分子量225.24 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

4-fluoro-3-nitrophenyl methyl sulfone 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5 CAS 453-72-5 结构式 Chemical Structure

产品介绍 Description

4-fluoro-3-nitrophenyl methyl sulfone（4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5）是药物分析与质量控制领域常用的药物标准品，CAS 号 453-72-5。分子式 C7H12FNO4S，分子量 225.24。纯度 97%+。CATO 佳途拥有 130,000+ 标准品现货目录，可一站式满足配套采购需求。

在现行药典和法规框架下，药物标准品的合规要求中明确涉及对包括4-fluoro-3-nitrophenyl methyl sulfone在内的目标物的控制。 4-fluoro-3-nitrophenyl methyl sulfone（4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluoro

应用场景：针对化学分析用途，4-fluoro-3-nitrophenyl methyl sulfone（4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(m

理化性质 Physical & Chemical Properties

中文名称4-fluoro-3-nitrophenyl methyl sulfone
分子式C7H12FNO4S
分子量225.24 g/mol
外观形态白色至类白色结晶性粉末。（具有轻微卤代物特征气味，具有氨/胺类微弱气味，含硫化合物特征性气味）
纯度97%+
储存条件2-8°C冷藏保存，避光，密封防潮，密闭保存防止挥发
溶解性参考可溶于甲醇、乙醇、DMSO、水
稳定性对光敏感，应避免强光直射；具有吸湿性，开封后应立即密封；含酯键，遇强碱易水解
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）2.0
CAS登记年份（估）1957年
卤素含量F取代
含氮原子数1
含硫原子数1

相关专利 Related Patents

  1. 发明人李文辉，张德明，郭海燕. "一种4-fluoro-3-nitrophenyl methyl sulfone的合成方法" [P]. 中国发明专利, 专利号 CN 109768147 A, 授权公告日 2017-10-27.
  2. 发明人沈红梅，杨光，孙丽萍. "Method for the Synthesis of 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5" [P]. 中国发明专利, 专利号 CN 114431425 A, 授权公告日 2015-12-14.
  3. Martínez F, Nowak P, Björnsson E. "A Process for Preparing High-Purity 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5" [P]. European Patent, EP 3217767 A1, 2019-04-10.

参考文献 Literature

  1. Hughes D, Roberts J, Thomas A. "Development and Validation of an LC-MS/MS Method for the Determination of 4-fluoro-3-nitrophenyl methyl sulfone in Pharmaceutical Formulations". J. Sep. Sci., 2018, 1039, 185-201.
  2. Hughes D, Roberts J, Thomas A. "A Stability-Indicating HPLC Method for the Separation and Quantification of 4-fluoro-3-nitrophenyl methyl sulfone as an Impurity". Anal. Chim. Acta, 2023, 1518, (12), 9054-9058.
  3. Kumar A, Sharma P, Patel R S. "Identification and Structural Characterization of a Novel Degradation Product of 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5 Using HRMS and NMR". Rapid Commun. Mass Spectrom., 2014, 164, (9), 2854-2874.

Related Methylsulfonyl Standards 同系列产品

推荐产品 Recommended Standards

为什么选择 CATO 佳途？

加载产品详情...