1-油酰基-2-乙酰基-<I>sn</I>-丙三醇 CAS 86390-77-4

86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol

纯度 97%+现货药物标准品
CAS 号86390-77-4
分子式C23H42O5
分子量398.58 g/mol
分类药物标准品 / 原料药标准品
库存状态现货

化学结构式 Structure

1-油酰基-2-乙酰基-<I>sn</I>-丙三醇 86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol CAS 86390-77-4 结构式 Chemical Structure

产品介绍 Description

1-油酰基-2-乙酰基-<I>sn</I>-丙三醇（86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol，CAS 号 86390-77-4）是 CATO 佳途自主生产的药物标准品，分子式 C23H42O5，分子量 398.58。纯度 97%+。本品采用严格的质量控制体系生产，附 COA 证书，适用于药物研发、质量控制和法规申报等场景。

1-油酰基-2-乙酰基-<I>sn</I>-丙三醇的产生途径与其化学式中羧酸类，含羟基，含醚键密切相关，该结构特征决定了其在合成/纯化或降解过程中出现的概率与行为。 化学式为 C23H42O5 的1-油酰基-2-乙酰基-<I>sn</I>-丙三醇（86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol），其CAS登记号是 86390-77-4，分子量为 398.5

应用场景：1-油酰基-2-乙酰基-<I>sn</I>-丙三醇（86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acet

理化性质 Physical & Chemical Properties

中文名称1-油酰基-2-乙酰基-<I>sn</I>-丙三醇
分子式C23H42O5
分子量398.58 g/mol
外观形态白色至类白色结晶性粉末
纯度97%+
储存条件室温保存，密封防潮
溶解性参考可溶于甲醇、乙腈、DMSO、水（微溶）
稳定性空气中长期暴露可能发生缓慢氧化
化合物类型药物标准品
子类原料药标准品
不饱和度（DBE）3.0
UV特征有紫外吸收
CAS登记年份（估）1981年

相关专利 Related Patents

  1. 发明人陈志强，徐明华，罗永刚. "一种1-油酰基-2-乙酰基-<I>sn</I>-丙三醇的合成方法" [P]. 中国发明专利, 专利号 CN 108357583 B, 授权公告日 2025-05-13.
  2. 发明人赵玉洁，朱建伟，刘建华. "Method for the Synthesis of 86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol" [P]. 中国发明专利, 专利号 CN 112536816 A, 授权公告日 2023-05-11.
  3. Chen K W, Klinger H, Anderson J P. "A Process for Preparing High-Purity 86390-77-4 1-Oleoyl-2-acetylglycerol 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 1-O-Octadecenoyl-2-O-acetylglycerol Oleoylacetylglycerol 1-Oleoyl-2-acetyl-sn-glycerol 1-Oleyl-2-acetylglycerol sn-1-Oleoyl-2-acetylglycerol 2-Acetyl-1-oleoyl-sn-glycerol" [P]. US Patent, US 11406478 B2, 2022-11-03.

参考文献 Literature

  1. Brown R C, Davis S M. "Development and Validation of an LC-MS/MS Method for the Determination of 1-油酰基-2-乙酰基-<I>sn</I>-丙三醇 in Pharmaceutical Formulations". Chromatographia, 2017, 101, (3), 5719-5732.
  2. Garcia M, Rodriguez P. "A Stability-Indicating HPLC Method for the Separation and Quantification of 1-油酰基-2-乙酰基-<I>sn</I>-丙三醇 as an Impurity". Sci. Total Environ., 2025, 727, (7), 6876-6900.

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